Evidence map›Paper›PMID 28358988›Full record

ArticleJournal of the Royal Society of Medicine2017

Trends in the incidence of chronic fatigue syndrome and fibromyalgia in the UK, 2001-2013: a Clinical Practice Research Datalink study.

Simon M Collin, Inger J Bakken, Irwin Nazareth, Esther Crawley, Peter D White

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of the Royal Society of Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06777667 (Impact of Resilience and Family Dynamics on Disease Severity in Women With Fibromyalgia), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06777667 completednot on this mapstarted 2024, after this paper: background citation

Impact of Resilience and Family Dynamics on Disease Severity in Women With Fibromyalgia: Comparison With Healthy Controls

Typeobservational_patient_registrySponsorAntalya Training and Research HospitalRan2024 to 2025Enrolled194ConditionsFibromyalgia, Resilience
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  13. Non-inflammatory pain in inflammatory arthritis.Rheumatology (Oxford, England) · 2023
    Review
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  19. Effectiveness a herbal medicine (Integrative medicine research · 2021
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Simon M Collin1 School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
Inger J Bakken2 Norwegian Institute of Public Health, 0403 Oslo, Norway.
Irwin Nazareth3 UCL Department of Primary Care and Population Health, UCL Royal Free Campus, London NW3 2PF, UK.
Esther Crawley1 School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
Peter D White4 Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
University of Bristol · GBNorwegian Institute of Public Health · NOQueen Mary University of London · GBUniversity College London · GB

Funding

Department of Health PDF-2013-06-011Department of Health SRF-2013-06-013
6 · The paper itself

Abstract

Objective Trends in recorded diagnoses of chronic fatigue syndrome (CFS, also known as 'myalgic encephalomyelitis' (ME)) and fibromyalgia (FM) in the UK were last reported more than ten years ago, for the period 1990-2001. Our aim was to analyse trends in incident diagnoses of CFS/ME and FM for the period 2001-2013, and to investigate whether incidence might vary by index of multiple deprivation (IMD) score. Design Electronic health records cohort study. Setting NHS primary care practices in the UK. Participants Participants: Patients registered with general practices linked to the Clinical Practice Research Datalink (CPRD) primary care database from January 2001 to December 2013. Main outcome measure Incidence of CFS/ME, FM, post-viral fatigue syndrome (PVFS), and asthenia/debility. Results The overall annual incidence of recorded cases of CFS/ME was 14.8 (95% CI 14.5, 15.1) per 100,000 people. Overall annual incidence per 100,000 people for FM was 33.3 (32.8-33.8), for PVFS 12.2 (11.9, 12.5), and for asthenia/debility 7.0 (6.8, 7.2). Annual incidence rates for CFS/ME diagnoses decreased from 17.5 (16.1, 18.9) in 2001 to 12.6 (11.5, 13.8) in 2013 (annual percent change -2.8% (-3.6%, -2.0%)). Annual incidence rates for FM diagnoses decreased from 32.3 (30.4, 34.3) to 27.1 (25.5, 28.6) in 2007, then increased to 38.2 (36.3, 40.1) per 100,000 people in 2013. Overall annual incidence of recorded fatigue symptoms was 2246 (2242, 2250) per 100,000 people. Compared with the least deprived IMD quintile, incidence of CFS/ME in the most deprived quintile was 39% lower (incidence rate ratio (IRR) 0.61 (0.50, 0.75)), whereas rates of FM were 40% higher (IRR 1.40 (0.95, 2.06)). Conclusion These analyses suggest a gradual decline in recorded diagnoses of CFS/ME since 2001, and an increase in diagnoses of fibromyalgia, with opposing socioeconomic patterns of lower rates of CFS/ME diagnoses in the poorest areas compared with higher rates of FM diagnoses.

Indexed as

Health Status DisparitiesPovertySocial ClassAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCohort StudiesFatigue Syndrome, ChronicFibromyalgiaHealthcare DisparitiesHumansIncidenceInfantChronic fatigue syndromediagnosisfibromyalgiageneral practiceincidence; fatiguemyalgic encephalomyelitispost-viral fatigueprimary care

Identifiers

PMID28358988
PMCPMC5499564
OpenAlexW2599912291

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.