ArticlePloS one2017
PCR diagnosis of tick-borne pathogens in Maharashtra state, India indicates fitness cost associated with carrier infections is greater for crossbreed than native cattle breeds.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Prevalence and determinants of bovine theileriosis in India: a meta-analysis and meta-regression.Tropical animal health and production · 2026Pooled it
- Prevalence of babesiosis in bovines of India: a meta-analytical approach for 30 years (1990-2019).The veterinary quarterly · 2023Pooled it
- Comprehensive evaluation of tick infestation dynamics and host response in Kankrej and Holstein Friesian crossbred cattle.Veterinary and animal science · 2026Article
- From Benign Parasite to Emerging Pathogen: A Review ofAnimals : an open access journal from MDPI · 2026Review
- Assessment of health conditions in Khmer native × Hariana crossbred cattle under a free-grazing system.Open veterinary journal · 2026Article
- Insights into the genetic diversity and population structure of prevalent Theileria orientalis in Bangladesh.PloS one · 2026Article
- Comparative evaluation of real-time polymerase chain reaction, conventional PCR and microscopy for detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Epidemiology and molecular characterization of Theileria annulata in ticks collected from cattle in the central part of Tamil Nadu, India.Parasitology research · 2023Article
- Guardians of the Herd: Molecular Surveillance of Tick Vectors Uncovers Theileriosis Perils in Large Ruminants.Microorganisms · 2023Article
- Molecular Detection and Identification of Piroplasm in Cattle from Kathmandu Valley, Nepal.Pathogens (Basel, Switzerland) · 2023Article
- Dynamics of Infections in Cattle andPathogens (Basel, Switzerland) · 2023Article
- Multiplex PCR for rapid differential diagnosis of co-prevalent species of Theileria (Theileria annulata and Theileria orientalis) in cattle.Parasitology research · 2023Article
- Article
- Epidemiology, haematology and molecular characterization of haemoprotozoon and rickettsial organisms causing infections in cattle of Jammu region, North India.BMC veterinary research · 2021Article
- Update on prevalence and distribution pattern of tick-borne diseases among humans in India: a review.Parasitology research · 2021Review
- The impact of tick-borne pathogen infection in Indian bovines is determined by host type but not the genotype of Theileria annulata.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019Article
- Ticks and accompanying pathogens of domestic and wild animals of Kerala, South India.Experimental & applied acarology · 2019Article
- First Molecular detection of Theileria annulata in Bangladesh.The Journal of veterinary medical science · 2019Article
- The Prevalence and Molecular Characterization of BovineIranian journal of parasitologyArticle
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tick-borne pathogens (TBP) are responsible for significant economic losses to cattle production, globally. This is particularly true in countries like India where TBP constrain rearing of high yielding Bos taurus, as they show susceptibility to acute tick borne disease (TBD), most notably tropical theileriosis caused by Theileria annulata. This has led to a programme of cross breeding Bos taurus (Holstein-Friesian or Jersey) with native Bos indicus (numerous) breeds to generate cattle that are more resistant to disease. However, the cost to fitness of subclinical carrier infection in crossbreeds relative to native breeds is unknown, but could represent a significant hidden economic cost. In this study, a total of 1052 bovine blood samples, together with associated data on host type, sex and body score, were collected from apparently healthy animals in four different agro-climatic zones of Maharashtra state. Samples were screened by PCR for detection of five major TBPs: T. annulata, T. orientalis, B. bigemina, B. bovis and Anaplasma spp.. The results demonstrated that single and co-infection with TBP are common, and although differences in pathogen spp. prevalence across the climatic zones were detected, simplistic regression models predicted that host type, sex and location are all likely to impact on prevalence of TBP. In order to remove issues with autocorrelation between variables, a subset of the dataset was modelled to assess any impact of TBP infection on body score of crossbreed versus native breed cattle (breed type). The model showed significant association between infection with TBP (particularly apicomplexan parasites) and poorer body condition for crossbreed animals. These findings indicate potential cost of TBP carrier infection on crossbreed productivity. Thus, there is a case for development of strategies for targeted breeding to combine productivity traits with disease resistance, or to prevent transmission of TBP in India for economic benefit.
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