Evidence map›Paper›PMID 28358339›Full record

ArticleMolecules (Basel, Switzerland)2017

Novel Palladium(II) Complexes that Influence Prominin-1/CD133 Expression and Stem Cell Factor Release in Tumor Cells.

Eva Fischer-Fodor, Roman Mikláš, Lucia Rišiaňová, Mihai Cenariu, Ioana-Georgeta Grosu, Piroska Virag, Maria Perde-Schrepler, Ciprian Tomuleasa, Ioana Berindan-Neagoe, Ferdinand Devínsky and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Nanomedicines in the treatment of colon cancer: a focus on metallodrugs.Drug delivery and translational research · 2022
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Eva Fischer-Fodor"I. Chiricuta" Institute of Oncology, Republicii 34-36, RO-400015 Cluj-Napoca, Romania. fischer.eva@iocn.ro.
Roman MiklášDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Kalinčiakova 8, 83104 Bratislava, Slovakia. virag.piroska@yahoo.com.
Lucia RišiaňováDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Kalinčiakova 8, 83104 Bratislava, Slovakia. pmariaida@yahoo.com.
Mihai CenariuBiotechnology Research Center, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania. ciprian.tomuleasa@umfcluj.ro.
Ioana-Georgeta GrosuNational Institute for Research and Development of Isotopic and Molecular Technologies, RO-400293 Cluj-Napoca, Romania. Ioana.neagoe@umfcluj.ro.
Piroska Virag"I. Chiricuta" Institute of Oncology, Republicii 34-36, RO-400015 Cluj-Napoca, Romania. miklas@fpharm.uniba.sk.
Maria Perde-Schrepler"I. Chiricuta" Institute of Oncology, Republicii 34-36, RO-400015 Cluj-Napoca, Romania. lucia.risianova@gmail.com.
Ciprian Tomuleasa"I. Chiricuta" Institute of Oncology, Republicii 34-36, RO-400015 Cluj-Napoca, Romania. devinsky@fpharm.uniba.sk.
Ioana Berindan-Neagoe"I. Chiricuta" Institute of Oncology, Republicii 34-36, RO-400015 Cluj-Napoca, Romania. Mihai.cenariu@usamvcluj.ro.
Ferdinand DevínskyDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Kalinčiakova 8, 83104 Bratislava, Slovakia. grosu.ioana@gmail.com.
Natalia MiklášováDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Kalinčiakova 8, 83104 Bratislava, Slovakia. miklasova@fpharm.uniba.sk.
Comenius University Bratislava · SKIuliu Hațieganu University of Medicine and Pharmacy · ROInstitute of Oncology Prof. Dr. Ion Chiricuta · RONational Institute for Research and Development of Isotopic and Molecular Technologies · ROUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New Pd(II) complexes of 1,7-bis(2-methoxyphenyl)hepta-1,6-diene-3,5-dione were synthesized and structurally characterized. The complexes were tested in vitro on human colon and hepatic carcinoma cell lines, normal hepatic cells and hematopoietic progenitor cells. Biological tests proved that Pd(II) complexes

Indexed as

AC133 AntigenCell Line, TumorCell ProliferationCell SurvivalColonic NeoplasmsDrug Screening Assays, AntitumorGene Expression Regulation, NeoplasticHT29 CellsHumansLiver NeoplasmsOrganometallic CompoundsPalladiumStem Cell FactorAC133 AntigenOrganometallic CompoundsPalladiumPROM1 protein, humanStem Cell Factorcolorectal cancercurcuminoidscytotoxicitypalladium complexesprominin-1 expressionstem cell factor

Identifiers

PMID28358339
PMCPMC6154565
OpenAlexW2602593919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.