Evidence map›Paper›PMID 28358321›Full record

ArticleMarine drugs2017

The Influence of Tetrodotoxin (TTX) on the Distribution and Chemical Coding of Caudal Mesenteric Ganglion (CaMG) Neurons Supplying the Porcine Urinary Bladder.

Ewa Lepiarczyk, Agnieszka Bossowska, Jerzy Kaleczyc, Marta Majewska, Sławomir Gonkowski, Mariusz Majewski

Abstract read
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In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ewa LepiarczykDepartment of Human Physiology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, 10-082 Olsztyn, Poland. ewa.lepiarczyk@uwm.edu.pl.
Agnieszka BossowskaDepartment of Human Physiology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, 10-082 Olsztyn, Poland. agnboss@uwm.edu.pl.
Jerzy KaleczycDepartment of Animal Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland. jerzy.kaleczyc@uwm.edu.pl.
Marta MajewskaDepartment of Human Physiology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, 10-082 Olsztyn, Poland. marta.majewska@uwm.edu.pl.
Sławomir GonkowskiDepartment of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn,10-719 Olsztyn, Poland. slawomir.gonkowski@uwm.edu.pl.
Mariusz MajewskiDepartment of Human Physiology, Faculty of Medical Sciences, University of Warmia and Mazury in Olsztyn, 10-082 Olsztyn, Poland. mariusz.majewski@uwm.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of micturition disorders creates a serious problem for urologists. Recently, new therapeutic agents, such as neurotoxins, are being considered for the therapy of urological patients. The present study investigated the chemical coding of caudal mesenteric ganglion (CaMG) neurons supplying the porcine urinary bladder after intravesical instillation of tetrodotoxin (TTX). The CaMG neurons were visualized with retrograde tracer Fast blue (FB) and their chemical profile was disclosed with double-labeling immunohistochemistry using antibodies against tyrosine hydroxylase (TH), neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP), somatostatin (SOM), calbindin (CB), galanin (GAL) and neuronal nitric oxide synthase (nNOS). It was found that in both the control (

Indexed as

AnimalsCalbindinsFemaleGalaninGanglia, SympatheticNeuronsNeuropeptide YNeurotoxinsNitric Oxide Synthase Type ISomatostatinSwineTetrodotoxinTyrosine 3-MonooxygenaseUrinary BladderVasoactive Intestinal PeptideCalbindinsGalaninNeuropeptide YNeurotoxinsNitric Oxide Synthase Type ISomatostatinTetrodotoxinTyrosine 3-MonooxygenaseVasoactive Intestinal Peptidecaudal mesenteric ganglionimmunohistochemistrypigtetrodotoxinurinary bladder

Identifiers

PMID28358321
PMCPMC5408247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.