Evidence map›Paper›PMID 28358089›Full record

ReviewNature2017

Exploiting non-covalent π interactions for catalyst design.

Andrew J Neel, Margaret J Hilton, Matthew S Sigman, F Dean Toste

Abstract readReview
In one paragraph

Review in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

193 citing papers in PubMed.

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  16. Size and Polarizability as Design Principles for Stereoselective Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  17. Article
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133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew J NeelChemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Margaret J HiltonDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112, USA.
Matthew S SigmanDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112, USA.
F Dean TosteChemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

Funding

Methods for Selective Organic Synthesis based on Ionic CatalystsR35GM118190 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI F. Dean Toste · 2016 to 2026
$6.7M
NIGMS NIH HHS R35 GM118190
6 · The paper itself

Abstract

Molecular recognition, binding and catalysis are often mediated by non-covalent interactions involving aromatic functional groups. Although the relative complexity of these so-called π interactions has made them challenging to study, theory and modelling have now reached the stage at which we can explain their physical origins and obtain reliable insight into their effects on molecular binding and chemical transformations. This offers opportunities for the rational manipulation of these complex non-covalent interactions and their direct incorporation into the design of small-molecule catalysts and enzymes.

Indexed as

Drug DesignModels, ChemicalAnionsCatalysisCationsEnzymesSmall Molecule LibrariesAnionsCationsEnzymesSmall Molecule Libraries

Identifiers

PMID28358089
PMCPMC5907483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.