ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019
Clinical performance of Rb-82 myocardial perfusion PET and Tc-99m-based SPECT in patients with extreme obesity.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 30 citations in OpenAlex.
- Improved assessment of coronary artery disease in obese patients with flurpiridaz-Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026Trial
- Advances in GPCR-Targeted PET Radiotracer Patents (2020-2025).Pharmaceuticals (Basel, Switzerland) · 2026Review
- Role of Computed Tomography and Other Non-Invasive and Invasive Imaging Modalities in Cardiac Allograft Vasculopathy.Journal of cardiovascular development and disease · 2025Review
- Efficacy of Diagnostic Testing of Suspected Coronary Artery Disease: A Contemporary Review.Cardiology · 2025Review
- Obesity: the perfect storm for heart failure.ESC heart failure · 2024Review
- Exponential dosing to standardize myocardial perfusion image quality with rubidium-82 PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The Role of Cardiac PET in Diagnosis and Prognosis of Ischemic Heart Disease: Optimal Modality Across Different Patient Populations.Current atherosclerosis reports · 2023Review
- Cost-effectiveness of 82-Rubidium PET myocardial perfusion imaging for the diagnosis of myocardial ischemia depending on the prevalence of coronary artery disease.EJNMMI research · 2023Article
- PET Image Denoising using a Deep-Learning Method for Extremely Obese Patients.IEEE transactions on radiation and plasma medical sciences · 2022Article
- Feasibility of exercise treadmillJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Review
- Diagnostic Accuracy of Myocardial Perfusion Imaging in Obese Diabetic Patients.Obesity surgery · 2021Article
- EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021Article
- The Newer, the Better; and May Be Not Good Enough?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- PET/CT Myocardial Perfusion Imaging Acquisition and Processing: Ten Tips and Tricks to Help You Succeed.Current cardiology reports · 2021Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Positron emission tomography, computed tomography and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Emerging Techniques for Cardiovascular PET.Cardiovascular innovations and applications · 2019Article
- Coronary Microvascular Dysfunction and Cardiovascular Risk in Obese Patients.Journal of the American College of Cardiology · 2018Observational
- SPECT but not PET remains as the working horse of the state of the art nuclear cardiac imaging laboratory: Con.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated the performance of stress imaging with technetium-99m-labeled tetrofosmin single-photon emission computed tomography (SPECT) and rubidium-82 positron emission tomography (PET) in patients with extreme obesity, defined as body mass index ≥40 kg/m
methodsWe identified patients with extreme obesity who underwent angiography in our center and either stress SPECT or PET within the previous six months. Cohorts of patients with extreme obesity and a <5% pretest likelihood of CAD who underwent SPECT (N = 25) or PET (N = 25) were also included.
resultsIn total, 108 patients who underwent SPECT (N = 57) or PET (N = 51) were identified. Scan interpretation was classified as definitely normal or abnormal in 83.3% of PET and 60.5% of SPECT scans, respectively (P < .01). PET demonstrated higher diagnostic accuracy and normalcy rate. PET was found to have higher specificity for the pooled cohort. Similar findings were observed using stenosis cut-offs of ≥50% and ≥70%.
conclusionsIn patients with extreme obesity, PET enabled more definitive scan interpretation with less artifact compared to SPECT. PET provided higher diagnostic accuracy and specificity in the detection of obstructive coronary artery disease.
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