Evidence map›Paper›PMID 28357782›Full record

ArticleJournal of endocrinological investigation2017

Psychological characteristics of Italian gender dysphoric adolescents: a case-control study.

A D Fisher, J Ristori, G Castellini, C Sensi, E Cassioli, A Prunas, M Mosconi, R Vitelli, D Dèttore, V Ricca and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Demographic and mental health profile of youth in a gender service: An African case series.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
  5. Pain mechanisms in the transgender individual: a review.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Suicidality in clinic-referred transgender adolescents.European child & adolescent psychiatry · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Suicidality among Gender Minority Youth: Analysis of 2017 Youth Risk Behavior Survey Data.Archives of suicide research : official journal of the International Academy for Suicide Research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A D FisherSexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy.
J RistoriSexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy.
G CastelliniPsychiatry Unit, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
C SensiPsychiatry Unit, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
E CassioliPsychiatry Unit, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
A PrunasDipartimento di Psicologia Milano, Università degli Studi di Milano-Bicocca, Milan, Italy.
M MosconiGender Identity Development Service, Hospital S. Camillo-Forlanini, Rome, Italy.
R VitelliDipartimento di Neuroscienze, Scienze Riproduttive ed Odontostomatologiche Università degli Studi di Napoli Federico II, Naples, Italy.
D DèttoreDepartment of Health Sciences, University of Florence, Florence, Italy.
V RiccaPsychiatry Unit, Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
M MaggiSexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy. m.maggi@dfc.unifi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGender dysphoria (GD) is associated with clinically significant distress and impairment in social, scholastic, and other important areas of functioning, especially when early onset is reported. The aim of the present study is to assess the psychopathological features associated with GD in adolescence, comparing a group of gender dysphoric adolescents (GDs) with a group of non-referred adolescents (NRs), in terms of body uneasiness, suicide risk, psychological functioning, and intensity of GD.

methodsA sample of 46 adolescents with GD and 46 age-matched NRs was evaluated (mean ± SD age = 16.00 ± 1.49 and 16.59 ± 1.11 respectively, p > 0.05). Subjects were asked to complete the Body Uneasiness Test (BUT) to explore body uneasiness, the Youth Self Report (YSR) to measure psychological functioning, the Multi-Attitude Suicide Tendency Scale (MAST) for suicide risk, and the Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults (GIDYQ-AA) for GD assessment.

resultsAdolescents with GD reported significantly higher levels of body uneasiness (BUT-GSI, F = 380.13, p < 0.0001), as well as a worse psychological functioning (YSR, F = 13.06 and p < 0.0001 for "total problem scale" and F = 12.53, p = 0.001 for "internalizing" scale) as compared to NRs. When YSR subscales were considered, GDs showed significantly higher scores in the "withdrawal/depression", "anxiety/depression", and "social problems" (all p < 0.0001). In addition, GDs showed significantly higher levels in the "attraction to death" and "repulsion by life" scales and lower scores in the "attraction to life" scale (all p < 0.0001). Finally, GIDYQ-AA score was significantly lower (meaning a higher level of gender dysphoria symptoms) in GDs vs. NRs (p < 0.0001).

conclusionsGD adolescents reported significantly higher body dissatisfaction and suicidal risk compared to NRs. In addition, results confirmed a significant impairment in social psychological functioning in adolescents with GD.

Indexed as

Self ReportAdolescentAdolescent BehaviorAnxietyCase-Control StudiesDepressionFemaleGender DysphoriaHumansItalyMaleAdolescentsBody uneasinessGender dysphoriaPsychological functioningSuicidal risk

Identifiers

PMID28357782

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.