ReviewJournal of materials science. Materials in medicine2017
Uterus transplantation and beyond.
Review in Journal of materials science. Materials in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03307356 (The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial
Who cites it
20 citing papers in PubMed.
- Mayer-Rokitansky-Kuster-Hauser Syndrome: From Radiological Diagnosis to Further Challenges-Review and Update.Diagnostics (Basel, Switzerland) · 2026Review
- Uterus transplantation: A bibliometric review of six-decade study from 1960 to 2024.Acta obstetricia et gynecologica Scandinavica · 2025Review
- A new bicornuate model of rat uterus transplantation.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration.Exploration (Beijing, China) · 2024Article
- Whole-organ decellularization of the human uterus and in vivo application of the bio-scaffolds in animal models.Journal of assisted reproduction and genetics · 2022Article
- The reproductive potential of uterus transplantation: future prospects.Acta bio-medica : Atenei Parmensis · 2022Article
- Endometrium as Control of Endometriosis in Experimental Research: Assessment of Sample Suitability.Diagnostics (Basel, Switzerland) · 2022Article
- Uterus transplantation in a sheep model: novel surgical technique with long-term survival and uterus vitality. First case series in Argentina.JBRA assisted reproduction · 2021Article
- First Successful Delivery after Uterus Transplantation in MHC-Defined Cynomolgus Macaques.Journal of clinical medicine · 2020Article
- Targeting connexins with Gap27 during cold storage of the human donor uterus protects against cell death.PloS one · 2020Article
- Allogeneic uterus transplantation in a rhesus model: A short-term graft viability study.PloS one · 2020Article
- Review
- What will the future hold for artificial organs in the service of assisted reproduction: prospects and considerations.Frontiers of medicine · 2019Review
- Long-Term Outcome and Rejection After Allogeneic Uterus Transplantation in Cynomolgus Macaques.Journal of clinical medicine · 2019Article
- Changes in the metabolic composition of storage solution with prolonged cold ischemia of the uterus.Journal of assisted reproduction and genetics · 2019Article
- Development of an efficient perfusion-based protocol for whole-organ decellularization of the ovine uterus as a human-sized model and in vivo application of the bioscaffolds.Journal of assisted reproduction and genetics · 2019Article
- Laparoscopic uterine graft procurement and surgical autotransplantation in ovine model.Scientific reports · 2019Article
- Uterine Transplant: A Risk to Life or a Chance for Life?Science and engineering ethics · 2019Article
- Uterus Allo-Transplantation in a Swine Model: Long-Term Graft Survival and Reproductive Function.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Intra- and Postoperative Blood Flow Monitoring in a Sheep Model of Uterus Transplantation.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uterus transplantation is today the only available treatment for absolute uterine factor infertility which is caused by either congenital/surgical uterine absence or that a present uterus is non-functioning. Structured animal-based research, from rodents to nonhuman primates, was the scientific basis for a successful introduction of uterus transplantation as a clinical procedure. The patient groups for uterus transplantation, the preclinical research and data from the published human cases will be covered herein. During recent years the concept of bioengineering of organs and tissues has emerged. Creation of a bioengineered uterus is in the initial research state, with experiments performed in rodents. The research that has been performed to create a bioengineered uterus will be summarized. In conclusion, uterus transplantation is now a clinical experimental procedure for treatment of uterine factor infertility. In parallel to the establishment of this combined assisted reproduction technique and transplantation procedure as a routine clinical procedure, we predict that uterus bioengineering will develop further towards introduction within the human setting, but that this process will take several years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.