Evidence map›Paper›PMID 28357536›Full record

ReviewJournal of neuro-oncology2017

Pediatric high-grade glioma: current molecular landscape and therapeutic approaches.

Steve Braunstein, David Raleigh, Ranjit Bindra, Sabine Mueller, Daphne Haas-Kogan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 177 citations in OpenAlex.

  1. Pooled it
  2. Association BetweenCancer control : journal of the Moffitt Cancer Center
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Molecular-targeted therapy for childhood low-grade glial and glioneuronal tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Extracranial metastasis of pediatric glioblastoma: case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  15. Updates on management of gliomas in the molecular age.World journal of clinical oncology · 2024
    Review
  16. Review
  17. "A tumour registry initiative".World neurosurgery: X · 2023
    Article
  18. Article
  19. Review
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Steve BraunsteinDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA. steve.braunstein@ucsf.edu.ORCID http://orcid.org/0000-0002-9841-9357
David RaleighDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Ranjit BindraDepartment of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.
Sabine MuellerDepartments of Neurology, Neurosurgery and Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Daphne Haas-KoganDepartment of Radiation Oncology, DFCI/BWH, Boston, MA, USA.
University of California, San Francisco · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-grade pediatric central nervous system glial tumors are comprised primarily of anaplastic astrocytomas (AA, WHO grade III) and glioblastomas (GBM, WHO grade IV). High-grade gliomas are most commonly diagnosed in the primary setting in children, but as in adults, they can also arise as a result of transformation of a low-grade malignancy, though with limited frequency in the pediatric population. The molecular genetics of high-grade gliomas in the pediatric population are distinct from their adult counterparts. In contrast to the adult population, high-grade gliomas in children are relatively infrequent, representing less than 20% of cases.

Indexed as

Central Nervous System NeoplasmsChildGliomaHumansNeoplasm GradingPediatric astrocytomaPediatric brain tumorPediatric glioblastoma

Identifiers

PMID28357536
OpenAlexW2598808425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.