Evidence map›Paper›PMID 28357339›Full record

ArticleMicrobial cell (Graz, Austria)2016

Learning epigenetic regulation from mycobacteria.

Sanjeev Khosla, Garima Sharma, Imtiyaz Yaseen

Open access · goldAbstract readComment
In one paragraph

Article in Microbial cell (Graz, Austria), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Epigenetic Reprogramming byAntibiotics (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Proteome Profiling ofACS omega · 2022
    Article
  8. Frontiers in molecular biosciences · 2022
    Article
  9. Review
  10. Genetic Diversity inAnnual review of genetics · 2020
    Review
  11. Host Epigenetics in Intracellular Pathogen Infections.International journal of molecular sciences · 2020
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sanjeev KhoslaCentre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India.
Garima SharmaCentre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India. ; Graduate Studies, Manipal University, Manipal, India.
Imtiyaz YaseenCentre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India. ; Graduate Studies, Manipal University, Manipal, India.
Centre for DNA Fingerprinting and Diagnostics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a eukaryotic cell, the transcriptional fate of a gene is determined by the profile of the epigenetic modifications it is associated with and the conformation it adopts within the chromatin. Therefore, the function that a cell performs is dictated by the sum total of the chromatin organization and the associated epigenetic modifications of each individual gene in the genome (epigenome). As the function of a cell during development and differentiation is determined by its microenvironment, any factor that can alter this microenvironment should be able to alter the epigenome of a cell. In the study published in Nature Communications (Yaseen 2015 Nature Communications 6:8922 doi: 10.1038/ncomms9922), we show that pathogenic

Indexed as

DNA methylationepigeneticsH3R42histone arginine methylationMycobacterium tuberculosisRv1988Rv2966c

Identifiers

PMID28357339
PMCPMC5349108
OpenAlexW2277303630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.