Evidence map›Paper›PMID 28357337›Full record

ArticleMicrobial cell (Graz, Austria)2016

The transcriptional repressor Sum1p counteracts Sir2p in regulation of the actin cytoskeleton, mitochondrial quality control and replicative lifespan in

Ryo Higuchi-Sanabria, Jason D Vevea, Joseph K Charalel, Maria L Sapar, Liza A Pon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell (Graz, Austria), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. NADCells · 2025
    Review
  2. Article
  3. Review
  4. In Vivo Imaging with Genetically Encoded Redox Biosensors.International journal of molecular sciences · 2020
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ryo Higuchi-SanabriaDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Jason D VeveaDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA. ; Current address: Department of Neuroscience, University of Wisconsin, Madison, WI, USA.
Joseph K CharalelDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA. ; Current address: Department of Genetics, Stanford University, Stanford, CA, USA.
Maria L SaparDepartment of Biological Sciences, Hunter College and The Graduate Center Biochemistry, Biology and Biopsychology and Behavioral Neuroscience Programs, CUNY, New York, NY 10065, USA. Current address: Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
Liza A PonDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA. ; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
Columbia University · USHunter College · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
NUTRITIONT32DK007647 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anthony W Ferrante, Lori M Zeltser · 1990 to 2026
$7.4M
MITOCHONDRIAL MOTILITY AND INHERITANCER01GM045735 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PON, LIZA A · 1993 to 2016
$4.2M
Mitochondrial-cytoskeletal interactions and agingR01GM096445 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PON, LIZA A · 2011 to 2014
$1.3M
NCI NIH HHS P30 CA013696NIDDK NIH HHS T32 DK007647NIGMS NIH HHS R01 GM045735NIGMS NIH HHS R01 GM096445
6 · The paper itself

Abstract

Increasing the stability or dynamics of the actin cytoskeleton can extend lifespan in

Indexed as

actin cytoskeletonagingmitochondriasirtuin

Identifiers

PMID28357337
PMCPMC5349106
OpenAlexW2317751077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.