ArticleMicrobial cell (Graz, Austria)2016
Physiology, phylogeny, and LUCA.
Article in Microbial cell (Graz, Austria), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- The Evolution of the First Code.Genes · 2026Review
- Chemical Evolution of Life on Earth.Genes · 2025Review
- A taxon-rich and genome-scale phylogeny of Opisthokonta.PLoS biology · 2024Article
- Identification of a deep-branching thermophilic clade sheds light on early bacterial evolution.Nature communications · 2023Article
- Biological Catalysis and Information Storage Have Relied onBiomolecules · 2023Review
- A Practical Guide to Design and Assess a Phylogenomic Study.Genome biology and evolution · 2022Article
- "Superwobbling" and tRNA-34 Wobble and tRNA-37 Anticodon Loop Modifications in Evolution and Devolution of the Genetic Code.Life (Basel, Switzerland) · 2022Review
- Determination of the Amino Acid Recruitment Order in Early Life by Genome-Wide Analysis of Amino Acid Usage Bias.Biomolecules · 2022Article
- Possible mechanisms of COInterface focus · 2019Article
- Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: a Workshop Report.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2019Review
- The last universal common ancestor between ancient Earth chemistry and the onset of genetics.PLoS genetics · 2018Review
- The GC Content as a Main Factor Shaping the Amino Acid Usage During Bacterial Evolution Process.Frontiers in microbiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genomes record their own history. But if we want to look all the way back to life's beginnings some 4 billion years ago, the record of microbial evolution that is preserved in prokaryotic genomes is not easy to read. Microbiology has a lot in common with geology in that regard. Geologists know that plate tectonics and erosion have erased much of the geological record, with ancient rocks being truly rare. The same is true of microbes. Lateral gene transfer (LGT) and sequence divergence have erased much of the evolutionary record that was once written in genomes, and it is not obvious which genes among sequenced genomes are genuinely ancient. Which genes trace to the last universal ancestor, LUCA? The classical approach has been to look for genes that are universally distributed. Another approach is to make all trees for all genes, and sift out the trees where signals have been overwritten by LGT. What is left ought to be ancient. If we do that, what do we find?
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.