Evidence map›Paper›PMID 28357321›Full record

ArticleMicrobial cell (Graz, Austria)2016

B cell-helping functions of gut microbial metabolites.

Chang H Kim

Open access · goldAbstract readComment
In one paragraph

Article in Microbial cell (Graz, Austria), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  3. Article
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  9. RETRACTED: Effect ofMicroorganisms · 2024
    Article
  10. Review
  11. Article
  12. Coaggregation of Asthma and Type 1 Diabetes in Children: A Narrative Review.International journal of molecular sciences · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Gut microbiome in type 1 diabetes: A comprehensive review.Diabetes/metabolism research and reviews · 2018
    Review
  18. Diet, Microbiota and Gut-Lung Connection.Frontiers in microbiology · 2018
    Review
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chang H KimLaboratory of Immunology and Hematopoiesis, Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, U.S.A. ; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, U.S.A. ; Purdue Institute for Inflammation, Immunology and Infectious Diseases; Purdue University, West Lafayette, IN 47907, U.S.A. ; Purdue Center for Cancer Research; Purdue University, West Lafayette, IN 47907, U.S.A.
Purdue University West Lafayette · US

Funding

FoxP3+ T cells of mucosal tissuesR01AI074745 · NIAID · PURDUE UNIVERSITY · PI KIM, CHANG H · 2008 to 2012
$1.7M
Therapeutic delivery of FoxP3+ T cells to the intestineR01DK076616 · NIDDK · PURDUE UNIVERSITY · PI KIM, CHANG H · 2008 to 2012
$1.5M
A multiphoton confocal microscope for biomedical research at Purdue UniversityS10RR028293 · NCRR · PURDUE UNIVERSITY · PI KIM, CHANG H · 2010 to 2010
$893k
Organ-specific migration of CD4+CD25+ regulatory T cellsR21AI063064 · NIAID · PURDUE UNIVERSITY WEST LAFAYETTE · PI KIM, CHANG H · 2005 to 2006
$406k
Migration and function of Th17 cells in the gutR56AI080769 · NIAID · PURDUE UNIVERSITY · PI KIM, CHANG H · 2009 to 2009
$336k
NCRR NIH HHS S10 RR028293NIAID NIH HHS R01 AI074745NIAID NIH HHS R21 AI063064NIAID NIH HHS R56 AI080769NIDDK NIH HHS R01 DK076616
6 · The paper itself

Abstract

Commensal microflora profoundly affects the host immune system. It has long been observed that commensal bacteria enhance antibody production in the host by producing antigens for B cell receptors (BCR) and ligands for Toll-like receptors (TLR). We recently reported that the microbial metabolites short-chain fatty acids (SCFAs) regulate the metabolism and gene expression in B cells to promote antibody production (Kim

Indexed as

acetateantibodiesB cellsbutyratecommensal bacteriadietary fiberimmunitypropionateshort-chain fatty acids

Identifiers

PMID28357321
PMCPMC5348987
OpenAlexW2524968973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.