Evidence map›Paper›PMID 28357245›Full record

ArticleMicrobial cell (Graz, Austria)2014

Genome evolution in yeast reveals connections between rare mutations in human cancers.

Xinchen Teng, J M Hardwick

Abstract readComment
In one paragraph

Article in Microbial cell (Graz, Austria), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cell death in genome evolution.Seminars in cell & developmental biology · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Xinchen TengCollege of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu Province 215123, PRChina. ; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205 USA.
J M HardwickW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cells are riddled with mutations. Less than one percent of these are thought to be mutations that drive cancer phenotypes. However, a recent study conducted on the yeast knockout collections by Teng

Indexed as

cancer progressiongenome evolutionsecondary mutationsyeast knockouts

Identifiers

PMID28357245
PMCPMC5354563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.