Evidence map›Paper›PMID 28357216›Full record

ArticleMicrobial cell (Graz, Austria)2014

Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion.

Marizela Delic, Alexandra B Graf, Gunda Koellensperger, Christina Haberhauer-Troyer, Stephan Hann, Diethard Mattanovich, Brigitte Gasser

Open access · goldAbstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Do fungi also undergo "ferroptosis"? A microscopic exploration of cellular death.Apoptosis : an international journal on programmed cell death · 2025
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  6. Establishment and application of an RNAi system inFrontiers in bioengineering and biotechnology · 2025
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  13. Review
  14. Article
  15. The Yeast eIF2 Kinase Gcn2 Facilitates HApplied and environmental microbiology · 2021
    Article
  16. Review
  17. In Vivo Imaging with Genetically Encoded Redox Biosensors.International journal of molecular sciences · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marizela DelicDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria.
Alexandra B GrafAustrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria. ; School of Bioengineering, University of Applied Sciences FH Campus Wien, Vienna, Austria.
Gunda KoellenspergerDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Department of Chemistry, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria.
Christina Haberhauer-TroyerDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Department of Chemistry, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria.
Stephan HannDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Department of Chemistry, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria.
Diethard MattanovichDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria.
Brigitte GasserDepartment of Biotechnology, BOKU University of Natural Resources and Life Sciences Vienna, Vienna, Austria. ; Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria.
Austrian Centre of Industrial Biotechnology (Austria) · ATBOKU University · ATHochschule Campus Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress, we investigate its role upon the production of secretory proteins, using the yeast

Indexed as

cellular redox regulationcytosolERglutathioneoxidative protein foldingPichia pastorisredox sensitive roGFP

Identifiers

PMID28357216
PMCPMC5349127
OpenAlexW2106258278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.