Evidence map›Paper›PMID 28357127›Full record

ArticlePharmacology research & perspectives2017

Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice.

Brian D Fink, Deng Fu Guo, Chaitanya A Kulkarni, Kamal Rahmouni, Robert J Kerns, William I Sivitz

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diabetes Mellitus, Mitochondrial Dysfunction and CaInternational journal of molecular sciences · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brian D FinkDepartment of Internal Medicine/Endocrinology University of Iowa and the Iowa City Veterans Affairs Medical Center Iowa City Iowa 52242.
Deng Fu GuoDepartment of Pharmacology University of Iowa Iowa City Iowa 52242.
Chaitanya A KulkarniDepartment of Pharmaceutical Sciences and Experimental Therapeutics University of Iowa Iowa City Iowa 52242.
Kamal RahmouniDepartments of Pharmacology and Internal Medicine University of Iowa Iowa City Iowa 52242.
Robert J KernsDepartment of Pharmaceutical Sciences and Experimental Therapeutics University of Iowa Iowa City Iowa 52242.
William I SivitzDepartment of Internal Medicine/Endocrinology University of Iowa and the Iowa City Veterans Affairs Medical Center Iowa City Iowa 52242.ORCID 0000-0002-7829-0189
University of Iowa · US

Funding

Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
PREDOCTORAL TRAINING PROGRAM IN BIOTECHNOLOGYT32GM008365 · NIGMS · UNIVERSITY OF IOWA · PI KERNS, ROBERT JOHN · 1990 to 2021
$3.8M
Mitochondrial respiratory uncoupling and the pathogenes*R01HL073166 · NHLBI · UNIVERSITY OF IOWA · PI SIVITZ, WILLIAM IRVING · 2003 to 2006
$877k
Mitochondrial-targeted CoQ: Metabolic and Redox Effects and role in DiabetesI01BX000285 · VA · IOWA CITY VA MEDICAL CENTER · PI SIVITZ, WILLIAM IRVING · 2011 to 2017
–
BLRD VA I01 BX000285NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL073166NIGMS NIH HHS T32 GM008365
6 · The paper itself

Abstract

We recently reported that mitoquinone (mitoQ, 500

Indexed as

Antioxidantscoenzyme Qleptinmitochondrianeuropeptide YObesity

Identifiers

PMID28357127
PMCPMC5368965
OpenAlexW2594179800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.