Evidence map›Paper›PMID 28357120›Full record

ArticlePharmacology research & perspectives2017

GABA

Emmanuel Sturchler, Xia Li, Maria de Lourdes Ladino, Kasia Kaczanowska, Michael Cameron, Patrick R Griffin, M G Finn, Athina Markou, Patricia McDonald

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. GABAMedComm · 2025
    Review
  3. Keeping the Balance: GABABrain sciences · 2022
    Review
  4. GABACurrent topics in behavioral neurosciences · 2022
    Article
  5. GABACurrent topics in behavioral neurosciences · 2022
    Review
  6. The GABAMolecules (Basel, Switzerland) · 2020
    Review
  7. Structural biology of GABANeuropharmacology · 2018
    Review
  8. KK-92A, a novel GABAPsychopharmacology · 2017
    Article
  9. GABAPharmacology research & perspectives · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Emmanuel SturchlerDepartment of Molecular Therapeutics The Scripps Research Institute 130 Scripps way Jupiter Florida 33458.
Xia LiDepartment of Psychiatry University of California San Diego 9500 Gilman Drive La Jolla California 92093.
Maria de Lourdes LadinoDepartment of Molecular Therapeutics The Scripps Research Institute 130 Scripps way Jupiter Florida 33458; Present address: School of Medicine Vanderbilt University 2215 Garland Ave Nashville Tennessee 37232.
Kasia KaczanowskaDepartment of Chemistry The Scripps Research Institute 10550 North Torrey Pines Road La Jolla California 92037; Present address: Department of Chemistry University of California San Diego, 9500 Gilman Drive La Jolla California 92093.
Michael CameronDepartment of Molecular Therapeutics The Scripps Research Institute 130 Scripps way Jupiter Florida 33458.
Patrick R GriffinDepartment of Molecular Therapeutics The Scripps Research Institute 130 Scripps way Jupiter Florida 33458.
M G FinnDepartment of Chemistry The Scripps Research Institute 10550 North Torrey Pines Road La Jolla California 92037; Present address: Georgia Institute of Technology School of Chemistry and Biochemistry 901 Atlantic Drive Atlanta Georgia 30332.
Athina MarkouDepartment of Psychiatry University of California San Diego 9500 Gilman Drive La Jolla California 92093.
Patricia McDonaldDepartment of Molecular Therapeutics The Scripps Research Institute 130 Scripps way Jupiter Florida 33458.
Scripps Research Institute · USUniversity of California, San Diego · US

Funding

Funct character of GABA_B receptor modulators, drug metabolism, pharmacokineticsU19DA026838 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MARKOU, ATHINA · 2010 to 2014
$7.3M
NIDA NIH HHS U19 DA026838
6 · The paper itself

Abstract

Positive modulation of the GABA

Indexed as

Allosteric modulatorbiased signalingfunctional selectivityGABAB receptorortholog selectivity

Identifiers

PMID28357120
PMCPMC5368958
OpenAlexW2600968540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.