ArticleMolecular and clinical oncology2017
Colon cancer metastasis to the mandibular gingiva with partial occult squamous differentiation: A case report and literature review.
Article in Molecular and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Oral Metastasis From Colorectal Adenocarcinoma: Report of a New Case and a Scoping Review.Case reports in dentistry · 2025Article
- Oral manifestations associated with gastrointestinal diseases - A review.Bioinformation · 2025Article
- A collision tumor composed of colon adenocarcinoma and large cell neuroendocrine carcinoma with gingival metastasis: a case report.Frontiers in oncology · 2025Article
- Hidden colon adenocarcinoma diagnosed from mouth metastasis: case report and literature review.World journal of surgical oncology · 2023Review
- Oral cavity colon adenocarcinoma metastases: case report with surgical approach and review of more than 30 years literature.Oral and maxillofacial surgery · 2021Review
- Metastasis of Colon Adenocarcinoma to Maxillary Gingiva and Palate.Iranian journal of otorhinolaryngology · 2020Article
- Anlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade.Cancer management and research · 2020Article
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4 authors.
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Abstract
Metastasis is the primary cause of death among patients with colon cancer. However, the number of available studies regarding oral cavity metastases from colon cancer is currently limited. We herein report an unusual case of a 60-year-old male patient who developed an oral cavity metastasis from colon cancer. A total of 12 clinical case studies reporting colon cancer metastases to the mandibular gingival region were also reviewed, with the aim to elucidate the clinical and pathological characteristics of this disease entity in order to improve clinical diagnosis and treatment. It was demonstrated that patients with oral cavity metastases from colon cancer were predominantly in the sixth or seventh decades of life. The mandible was the main site of metastatic tumors to the oral cavity, while the occurrence of gingival metastases was comparatively rare. Moreover, the diagnoses of an oral metastatic tumor and primary colon cancer were often synchronous and were frequently accompanied with metastases to other organs. Several key aspects were suggested that should be accounted for when diagnosing colon cancer patients, including focusing attention to oral symptoms when examining cancer patients, utilizing a multidisciplinary approach for differential diagnosis and utilizing postoperative pathological examination to accurately diagnose the type of tumor and optimize the efficacy of treatment.
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