Evidence map›Paper›PMID 28357061›Full record

ArticleTherapeutic advances in infectious disease2017

Oral mucositis caused by

Célia F Rodrigues, Mariana Henriques

Open access · bronzeAbstract read
In one paragraph

Article in Therapeutic advances in infectious disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of Antifungal Combinations in Difficult to TreatJournal of fungi (Basel, Switzerland) · 2021
    Review
  7. Antibiotics (Basel, Switzerland) · 2020
    Review
  8. Management ofJournal of clinical medicine · 2020
    Review
  9. Observational
  10. Inflammatory Cell Recruitment inJournal of clinical medicine · 2019
    Article
  11. Review
  12. Article
  13. Antagonistic Interaction ofFrontiers in microbiology · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Célia F RodriguesCentre of Biological Engineering (CEB), Laboratório de Investigação em Biofilmes Rosário Oliveira (LIBRO), University of Minho, Braga, Portugal.
Mariana HenriquesCentre of Biological Engineering (CEB), Laboratório de Investigação em Biofilmes Rosário Oliveira (LIBRO), University of Minho, 4710-057 Braga, Portugal.
University of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMATERIALS AND

methodsRoutine clinical 30 or 40 mg/l doses of Flu were applied to

resultsThe results showed that this combination effectively promoted the degradation of the biofilm network, but unfortunately, also stimulated the growth of the yeasts population due to release of several glucose monomers during β-glucans hydrolysis. DISCUSSION: AA lead to the hydrolysis of the β-glucans of the matrix, liberating glucose molecules which are used as carbon souce by the yeasts, thus suppressing the desired antifungal effect of the drug combination with Flu.

conclusionsUnlike to what happens in treatment of bacterial infection, AA should not be used together with Flu in the treating oral mucositis caused by

Indexed as

ascorbic acidbiofilm matrixCandida glabratafluconazoleinfectionresistance

Identifiers

PMID28357061
PMCPMC5360294
OpenAlexW2588653380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.