Evidence map›Paper›PMID 28357027›Full record

ReviewOxidative medicine and cellular longevity2017

Exercise Modifies the Gut Microbiota with Positive Health Effects.

Vincenzo Monda, Ines Villano, Antonietta Messina, Anna Valenzano, Teresa Esposito, Fiorenzo Moscatelli, Andrea Viggiano, Giuseppe Cibelli, Sergio Chieffi, Marcellino Monda and 1 more

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 362 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
362citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05567653 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of 3-month Probiotic Mix Supplementation (L. Helveticus R-0052, B. Longum R-0175) on Gut Microbiota and Metabolome, Endocannabinoid and Immune Systems Activation, Along With Symptoms of Fatigue in Professional Dancers

TypeinterventionalSponsorPoznan University of Physical EducationRan2022 to 2023Enrolled26ConditionsFatigue, Stress, JobArmsLactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress), Starch (placebo)
NCT06408610 nacompletednot on this mapstarted 2024, after this paper: background citation

Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and Glucagon Like Peptide Hormone in Irritable Bowel Syndrome

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled66ConditionsIrritable Bowel Syndrome, Obesity, DysbiosisArmsmoderate intensity continuous training
NCT07082582 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Investigating in Humans the Impact of Training Status on Dietary Consumption With Direct Measurement of Ingestive Behaviour

TypeobservationalSponsorMichele SerraRan2024 to 2026Enrolled60ConditionsFood Intake Regulation, Training Status
3 · Its place in the literature

Who cites it

362 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impacts of Lifestyle and Microbiota-Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  3. Pooled it
  4. Microbiome and well-being: a meta-analysis.NPJ biofilms and microbiomes · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. The association between the gut microbiome and fatigue in individuals living with cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Article
  17. Nurturing gut health: A comprehensive framework.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  18. Review
  19. Review
  20. Review

302 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vincenzo MondaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Ines VillanoDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Antonietta MessinaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Anna ValenzanoDepartment of Clinical and Experimental Medicine University of Foggia, Foggia, Italy.
Teresa EspositoDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Fiorenzo MoscatelliDepartment of Clinical and Experimental Medicine University of Foggia, Foggia, Italy.
Andrea ViggianoDepartment of Medicine, Surgery, and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
Giuseppe CibelliDepartment of Clinical and Experimental Medicine University of Foggia, Foggia, Italy.
Sergio ChieffiDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Marcellino MondaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy.
Giovanni MessinaDepartment of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Second University of Naples, Naples, Italy; Department of Clinical and Experimental Medicine University of Foggia, Foggia, Italy.ORCID 0000-0002-0011-867X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gastrointestinal tract (GIT) is inhabited by a wide cluster of microorganisms that play protective, structural, and metabolic functions for the intestinal mucosa. Gut microbiota is involved in the barrier functions and in the maintenance of its homeostasis. It provides nutrients, participates in the signaling network, regulates the epithelial development, and affects the immune system. Considering the microbiota ability to respond to homeostatic and physiological changes, some researchers proposed that it can be seen as an endocrine organ. Evidence suggests that different factors can determine changes in the gut microbiota. These changes can be both quantitative and qualitative resulting in variations of the composition and metabolic activity of the gut microbiota which, in turn, can affect health and different disease processes. Recent studies suggest that exercise can enhance the number of beneficial microbial species, enrich the microflora diversity, and improve the development of commensal bacteria. All these effects are beneficial for the host, improving its health status. In this paper, we intend to shed some light over the recent knowledge of the role played by exercise as an environmental factor in determining changes in microbial composition and how these effects could provide benefits to health and disease prevention.

Indexed as

ExerciseGastrointestinal MicrobiomeGastrointestinal TractHumansInflammatory Bowel DiseasesProbiotics

Identifiers

PMID28357027
PMCPMC5357536

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.