Evidence map›Paper›PMID 28356882›Full record

ArticleJournal of medical biochemistry2016

Protective Role of Maternal P.VAL158MET Catechol-O-Methyltransferase Polymorphism against Early-Onset Preeclampsia and its Complications.

Tijana Krnjeta, Ljiljana Mirković, Svetlana Ignjatović, Dragana Tomašević, Jelena Lukić, Drina Topalov, Ivan Soldatović, Nada Majkić-Singh

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Catechol-O-methyltransferase and Pregnancy Outcome: an Appraisal in Rat.Reproductive sciences (Thousand Oaks, Calif.) · 2021
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tijana KrnjetaRoche d.o.o. Serbia BU Diagnostics, Belgrade, Serbia.
Ljiljana MirkovićClinic of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia, and University of Belgrade - Faculty of Medicine, Belgrade, Serbia.
Svetlana IgnjatovićCenter for Medical Biochemistry, Clinical Center of Serbia, Belgrade, Serbia, and Department of Medical Biochemistry, University of Belgrade - Faculty of Pharmacy, Belgrade, Serbia.
Dragana TomaševićLaboratory for Biochemistry and Molecular Diagnostics »Konzilijum«, Belgrade, Serbia.
Jelena LukićLaboratory for Biochemistry and Molecular Diagnostics »Konzilijum«, Belgrade, Serbia.
Drina TopalovLaboratory for Biochemistry and Molecular Diagnostics »Konzilijum«, Belgrade, Serbia.
Ivan SoldatovićUniversity of Belgrade - Faculty of Medicine, Belgrade, Serbia.
Nada Majkić-SinghSociety of Medical Biochemistry of Serbia, Belgrade, Serbia.
University of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUp until now there have been contradictory data about the association between p.Val158Met catechol-O-methyltransferase (COMT) polymorphism and risk of preeclampsia (PE). The goal of this study was to assess the potential correlation between p.Val158Met

methodsThe study included 47 early-onset PE patients and 47 control cases. Forty-seven early-onset PE patients were grouped by disease severity (33 patients with a severe form and 14 patients without severe features) and secondly by size for gestational age (12 patients with appropriate-for-gestational-age (AGA) and 35 patients with SGA size). p.Val158Met polymorphism was genotyped by PCR-RFLP analysis.

resultsAllele analysis showed significant difference in

conclusions

Indexed as

COMTearly-onset preeclampsiapolymorphismsevereSGA

Identifiers

PMID28356882
PMCPMC5346809
OpenAlexW2338031658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.