ArticleActa medica Lituanic2016
Fatal pulmonary complication during induction therapy in a patient with ANCA-associated vasculitis.
Article in Acta medica Lituanic, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- Clinical features and risk factors of invasive pulmonary aspergillosis in interstitial lung disease patients.BMC pulmonary medicine · 2024Article
- A case of invasive pulmonary aspergillosis during treatment for acute exacerbation of interstitial lung disease.Infectious disease reports · 2018Article
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10 authors at 1 institution in 1 country.
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Abstract
ANCA-associated vasculitis (AAV) is an inflammatory systemic disorder affecting small to medium sized vessels and likely leading to any organ dysfunction. Adequate treatment is important to avoid mortality or severe organ damage. In most cases initial treatment (induction therapy) allows to achieve remission. Induction therapy leads to immunosuppression and may cause severe infections. However, in vasculitis patients even an intensive immunosuppressive therapy is rarely complicated by an invasive fungal infection. We present a case in a 29-year old male patient with newly diagnosed AAV. He suffered a fatal pulmonary complication of the induction immunosuppressive treatment. Pathological (infectious) changes in the lungs were misinterpreted as progression of the vasculitis and he died due to disseminated angioinvasive aspergillosis. A clinical course, imaging and histopathology of this case are described and discussed.
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