ArticleActa medica Lituanic2016
Hypoplastic left heart syndrome: a review.
Article in Acta medica Lituanic, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Current foetal cardiology practice in Italian centres: a survey among SICP members.International journal of cardiology. Congenital heart disease · 2026Article
- ValveFit: An analysis-suitable B-spline-based surface fitting framework for patient-specific modeling of tricuspid valves.Computer methods in applied mechanics and engineering · 2026Article
- Long-term neurodevelopmental outcomes in children with hypoplastic left heart syndrome.Annals of medicine and surgery (2012) · 2025Review
- Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients.Journal of the Royal Society, Interface · 2025Article
- First report of hypoplastic left heart syndrome in 3p- syndrome and review of candidate genes.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025Review
- Effects of cardiac growth on electrical dyssynchrony in the single ventricle patient.Computer methods in biomechanics and biomedical engineering · 2024Article
- Cardiac fibroma presenting as hypoplastic left heart syndrome in a foetus: causal or coincidental?BMJ case reports · 2024Review
- Aortic Valve Embryology, Mechanobiology, and Second Messenger Pathways: Implications for Clinical Practice.Journal of cardiovascular development and disease · 2024Review
- Integrating mechanical cues with engineered platforms to explore cardiopulmonary development and disease.iScience · 2023Review
- Case Report: 5 Cases of Variant Hypoplastic Left Heart Syndrome Diagnosed on Prenatal Fetal Ultrasound.The American journal of case reports · 2023Article
- Assessment of left atrial deformation in patients with total anomalous pulmonary venous connection by two-dimensional speckle-tracking echocardiography.Heart and vessels · 2023Article
- Cell-based therapy to boost right ventricular function and cardiovascular performance in hypoplastic left heart syndrome: Current approaches and future directions.Seminars in perinatology · 2023Review
- A computational study of aortic reconstruction in single ventricle patients.Biomechanics and modeling in mechanobiology · 2023Article
- Article
- Tissue engineering: Relevance to neonatal congenital heart disease.Seminars in fetal & neonatal medicine · 2022Review
- Extracellular matrix and cyclic stretch alter fetal cardiomyocyte proliferation and maturation in a rodent model of heart hypoplasia.Frontiers in cardiovascular medicine · 2022Article
- Hypoplastic left heart syndrome (HLHS): molecular pathogenesis and emerging drug targets for cardiac repair and regeneration.Expert opinion on therapeutic targets · 2021Review
- Role of gated cardiac computed tomographic angiography in the evaluation of postsurgical complications after stage I Norwood procedure and its implications on management: a comparative study with two-dimensional echocardiography.Pediatric radiology · 2021Article
- The immune system in infants: Relevance to xenotransplantation.Pediatric transplantation · 2020Review
- Hypoplastic left heart syndrome: From bedside to bench and back.Journal of molecular and cellular cardiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypoplastic left heart syndrome (HLHS) is an etiologically multifactorial congenital heart disease affecting one in 5,000 newborns. Thirty years ago there were no treatment options for this pathology and the natural course of the disease led to death, usually within the first weeks of life. Recently surgical palliative techniques have been developed allowing for a five-year survival in more than half the cases. MATERIALS AND
methodsWe reviewed literature available on HLHS, specifically its anatomy, embryology and pathophysiology, and treatment. The Pubmed and ClinicalKey databases were searched using the key words
resultsThere are three possible directions for therapy in newborns with HLHS: orthotopic heart transplantation, staged surgical palliation and palliative non-surgical treatment or
conclusionsThe superior mode of treatment is not yet clear and the management must be based on each individual case, the experience of each clinic, as well as the financial aspects and will of the patient's parents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.