Evidence map›Paper›PMID 28356764›Full record

ArticleJournal of asthma and allergy2017

Study of nasal exhaled nitric oxide levels in diagnosis of allergic rhinitis in subjects with and without asthma.

Sy Duong-Quy, Thuc Vu-Minh, Thong Hua-Huy, Tram Tang-Thi-Thao, Khiet Le-Quang, Dinh Tran-Thanh, Nhu Doan-Thi-Quynh, Nhat-Nam Le-Dong, Timothy J Craig, Anh-Tuan Dinh-Xuan

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Nasal nitric oxide measurement in allergic rhinitis and non-allergic rhinitis: a meta-analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Arginase Isoform Expression in Chronic Rhinosinusitis.Journal of clinical medicine · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Sy Duong-QuyDepartment of Respiratory Physiology, Cochin Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France; Department of Medicine, Penn State University, Hershey, PA, USA; Bio-Medical Research Center, Lam Dong Medical College, Dalat.
Thuc Vu-MinhDepartment of Immuno-Allergology, ENT National Institute, Hanoi, Vietnam.
Thong Hua-HuyDepartment of Respiratory Physiology, Cochin Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France.
Tram Tang-Thi-ThaoBio-Medical Research Center, Lam Dong Medical College, Dalat.
Khiet Le-QuangBio-Medical Research Center, Lam Dong Medical College, Dalat.
Dinh Tran-ThanhBio-Medical Research Center, Lam Dong Medical College, Dalat.
Nhu Doan-Thi-QuynhBio-Medical Research Center, Lam Dong Medical College, Dalat.
Nhat-Nam Le-DongDepartment of Pulmonology, St Elisabeth Hospital, Namur, Belgium.
Timothy J CraigDepartment of Medicine, Penn State University, Hershey, PA, USA.
Anh-Tuan Dinh-XuanDepartment of Respiratory Physiology, Cochin Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France.
Bio-Medical Science (South Korea) · KRDélégation Paris 5 · FRPenn State Milton S. Hershey Medical Center · USQueen Elisabeth Medical Foundation · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe measure of fractional exhaled nitric oxide (FENO) in the airways is a useful tool to guide the diagnosis and titration of inhaled corticosteroids in patients with asthma. However, its role in diagnosis of allergic rhinitis (AR), especially in subjects with asthma, is not well established.

objectiveTo study the cutoff of nasal FENO in the diagnosis of subjects with AR and AR-asthma compared to age-matched subjects without AR or asthma and its correlations with the clinical and functional characteristics.

methodsThe study was cross sectional and descriptive. Subjects were grouped into control subjects, AR, and AR-asthma, based on the inclusion criteria. Exhaled NO (nasal FENO, bronchial FENO, and alveolar concentration of NO) was measured by multiple flow electro-luminescence device.

resultsSix hundred twenty-eight subjects were included: 217 control subjects (children: n=98, 10±4 years; adults: n=119, 50±16 years), 168 subjects with AR (children: n=54, 10±3 years; adults: n=114, 49±15 years), and 243 subjects with AR-asthma (children: n=115, 10±3 years; adults: n=128, 51±14 years). Nasal peak inspiratory flow and peak expiratory flow were lower in subjects with AR and AR-asthma than in control subjects (

conclusionNasal FENO measurement is a useful technique for the diagnosis of AR in subjects with and without asthma.

Indexed as

allergic rhinitisasthmaFENOnasal FENOnitric oxideNO

Identifiers

PMID28356764
PMCPMC5367560
OpenAlexW2600778706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.