Evidence map›Paper›PMID 28356734›Full record

ArticleInternational journal of nanomedicine2017

Therapeutic effects of proteoliposomes on X-linked chronic granulomatous disease: proof of concept using macrophages differentiated from patient-specific induced pluripotent stem cells.

Julie Brault, Guillaume Vaganay, Aline Le Roy, Jean-Luc Lenormand, Sandra Cortes, Marie José Stasia

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Frontiers in immunology · 2022
    Review
  4. Review
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  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Julie BraultUMR CNRS 5525, University of Grenoble Alpes, Grenoble, France; CGD Diagnosis and Research Centre, University Hospital Centre of Grenoble Alpes, Grenoble, France.
Guillaume VaganaySynthelis SAS, La Tronche, France.
Aline Le RoyIBS, University of Grenoble Alpes, Grenoble, France; CNRS, IBS, University Grenoble Alpes, Grenoble, France; CEA, IBS, University of Grenoble Alpes, Grenoble, France.
Jean-Luc LenormandUMR CNRS 5525, University of Grenoble Alpes, Grenoble, France.
Sandra CortesSynthelis SAS, La Tronche, France.
Marie José StasiaUMR CNRS 5525, University of Grenoble Alpes, Grenoble, France; CGD Diagnosis and Research Centre, University Hospital Centre of Grenoble Alpes, Grenoble, France.
Centre National de la Recherche Scientifique · FRExelis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic granulomatous disease (CGD) is a rare inherited immunodeficiency due to dysfunction of the phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex leading to severe and recurrent infections in early childhood. The main genetic form is the X-linked CGD leading to the absence of cytochrome

Indexed as

Cell DifferentiationCandidaCell MembraneChild, PreschoolGenetic Diseases, X-LinkedGranulomatous Disease, ChronicHumansInduced Pluripotent Stem CellsMacrophagesNADPH OxidasesPhagocytosisProtein SubunitsProteolipidsReactive Oxygen SpeciesNADPH OxidasesProtein SubunitsProteolipidsproteoliposomesReactive Oxygen Specieschronic granulomatous diseaseinduced pluripotent stem cellsmacrophagesNADPH oxidaseprotein therapyproteoliposomes

Identifiers

PMID28356734
PMCPMC5367562
OpenAlexW2599406427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.