ArticleIndian journal of nephrology
Pregnancy-related acute kidney injury: An analysis of 165 cases.
Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and trends of pregnancy-related acute kidney injury in sub-Saharan Africa: a systematic review and meta-analysis.Journal of nephrology · 2025Pooled it
- Pattern and Outcome Trends in Pregnancy Related Acute Kidney Injury over 35 years: A study of 2,275 cases.Pakistan journal of medical sciences · 2026Article
- Article
- Spectrum of Pregnancy-Related Acute Kidney Injury in Obstetric Patients: A Retrospective Study.Journal of obstetrics and gynaecology of India · 2026Article
- Pregnancy-associated acute kidney injury - consensus report of the 32nd Acute Disease Quality Initiative workgroup.Nature reviews. Nephrology · 2025Article
- Pregnancy-Related Acute Kidney Injury: Causes and Its Impact on Perinatal Outcomes-A Systematic Review.Journal of clinical medicine · 2025Review
- Article
- Outcomes of obstetric versus non-obstetric acute kidney injury: insights from an Indian tertiary care centre.BMC nephrology · 2025Observational
- Maternal Mortality due to Pregnancy-Related Acute Kidney Injury (PRAKI); A Study of the Epidemiological Factors and Possible Solutions.Journal of obstetrics and gynaecology of India · 2025Article
- Pregnancy Related Acute Kidney Injury: An Exigent Cause of Chronic Kidney Disease in Developing Countries.Journal of obstetrics and gynaecology of India · 2024Article
- Prerenal Acute Kidney Injury is Still the Most Important Cause for Dialysis in an Obstetric Critical Care Referral Unit of North India: A 3 Year Retrospective Study.Journal of obstetrics and gynaecology of India · 2024Article
- Article
- Clinical and Paraclinical Features in Pregnancies Associated With Renal Impairment Due to Hypertensive Complications.Cureus · 2024Article
- Risk factors and fetomaternal outcome in pregnancy-related acute kidney injury.Journal of family medicine and primary care · 2023Article
- Clinical characteristics and prognosis of pregnancy-related acute kidney injury: a case series study.International urology and nephrology · 2023Article
- Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum.Frontiers in medicine · 2023Review
- Etiology of Pregnancy-related Acute Kidney Injury among Obstetric Patients in India: A Systematic Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Kidney-placenta crosstalk in health and disease.Clinical kidney journal · 2022Review
- Role of renal replacement therapy in pregnancy related acute kidney injury and its outcome.Journal of family medicine and primary care · 2022Article
- Renal Outcomes of Pregnancy-Related Acute Kidney Injury: a Single Centre Experience in India.Maedica · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy-related acute kidney injury (PRAKI) contributes to 3-7% of overall acute kidney injury (AKI) cases in Indian subcontinent. The aim of this study was to determine the outcomes of PRAKI and risk factors associated with renal injury and maternal mortality. One hundred and sixty-five patients with PRAKI, seen at M. S. Ramaiah Medical College between 2005 and 2014, were included in this, observational study. AKI was analyzed in terms of maximal stage of renal injury attained as per Risk, Injury, Failure, Loss of function, and End-stage renal disease (RIFLE) criteria. Outcomes included requirement for renal replacement therapy (RRT), maternal, and fetal mortality. Incidence of PRAKI was 1.56%, and the mean age of the study population was 25 years. Fifty percent of the patients were diagnosed with PRAKI during their first pregnancy. PRAKI was observed most commonly in the postpartum period (60%), followed by third trimester (32%); as per RIFLE criteria, failure was seen in 36% and injury in 34%. Thirty percent of cases required RRT. Sepsis (59%), pre-eclampsia, and eclampsia (56%) were the leading causes of PRAKI, while sepsis was the leading cause of maternal mortality. Maternal and fetal mortality were 20% and 22%, respectively. In univariate analysis, shock, hemorrhage requiring transfusion of >5 units packed red blood cells, oliguria, and "Loss" category of RIFLE were significantly associated with mortality. Majority of the patients (57%) required Intensive Care Unit care with a mean duration of admission at 7.3 days, and 75% was diagnosed with AKI at the time of admission. We report the lowest incidence of PRAKI in contemporary Indian literature. PRAKI was associated with high maternal and fetal mortality, with sepsis being the leading cause. No association was noted between mortality and initial stages of RIFLE criteria.
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