Observational studyHypertension research : official journal of the Japanese Society of Hypertension2017
Ejection time: influence of hemodynamics and site of measurement in the arterial tree.
Observational study in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Automated measurement of left ventricular ejection time via contactless suprasternal notch laser vibrometry.Scientific reports · 2026Article
- Dual-Graded Microstructure Engineering for Flexible Piezoresistive Sensors with High Sensitivity and Broad Linear Range in Physiological Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique.BMC anesthesiology · 2024Article
- Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart.Frontiers in cardiovascular medicine · 2023Article
- A comparison between left ventricular ejection time measurement methods during physiological changes induced by simulated microgravity.Experimental physiology · 2022Article
- Arterial path length estimation for heart-to-brachium pulse wave velocity.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Brachial-ankle pulse wave velocity, cardio-ankle vascular index, and prognosis.Vascular health and risk management · 2018Review
- Difference between ejection times measured at two different peripheral locations as a novel marker of vascular stiffness.PloS one · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The left ventricular ejection time is routinely measured from a peripheral arterial waveform. However, the arterial waveform undergoes constant transformation as the pulse wave propagates along the arterial tree. Our goal was to determine if the left ventricular ejection time measured peripherally in the arterial tree accurately reflected the ejection time measured through the aortic valve. Moreover, we examined/accessed the modulating influence of hemodynamics on ejection time measurements. Continuous wave Doppler waveform images through the aortic valve and the simultaneously obtained radial artery pressure waveforms were analyzed to determine central and peripheral ejection times, respectively. The peripheral ejection time was significantly longer than the simultaneously measured central ejection time (174.5±25.2 ms vs. 120.7±14.4 ms; P<0.0001; 17.4±8.7% increase). Moreover, the ejection time prolongation was accentuated at lower blood pressures, lower heart rate and lower pulse wave velocity. The time difference between centrally and peripherally measured ejection times likely reflects intrinsic vascular characteristics. Moreover, given that the ejection time also depends on blood pressure, heart rate and pulse wave velocity, peripherally measured ejection times might need to be adjusted to account for changes in these variables.
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