ArticleProceedings. Biological sciences2017
Speed dependency in α-motoneuron activity and locomotor modules in human locomotion: indirect evidence for phylogenetically conserved spinal circuits.
Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of the usefulness of magnetic resonance imaging in predicting the gait ability of stroke patients.Scientific reports · 2021Pooled it
- Progress in spinal cord organoid research: advancing understanding of neural development, disease modelling, and regenerative medicine.Biomaterials translational · 2024Review
- Different functional networks underlying human walking with pulling force fields acting in forward or backward directions.Scientific reports · 2023Article
- Unraveling age-related impairment of the neuromuscular system: exploring biomechanical and neurophysiological perspectives.Frontiers in physiology · 2023Review
- Sensory modulation of gait characteristics in human locomotion: A neuromusculoskeletal modeling study.PLoS computational biology · 2021Article
- Plasticity of muscle synergies through fractionation and merging during development and training of human runners.Nature communications · 2020Article
- Intra-limb and muscular coordination during walking on slopes.European journal of applied physiology · 2020Article
- Emergence of Different Gaits in Infancy: Relationship Between Developing Neural Circuitries and Changing Biomechanics.Frontiers in bioengineering and biotechnology · 2020Review
- Differential activation of lumbar and sacral motor pools during walking at different speeds and slopes.Journal of neurophysiology · 2019Article
- Cortical Correlates of Locomotor Muscle Synergy Activation in Humans: An Electroencephalographic Decoding Study.iScience · 2019Article
- Variant and Invariant Spatiotemporal Structures in Kinematic Coordination to Regulate Speed During Walking and Running.Frontiers in computational neuroscience · 2019Article
- Spinal control of muscle synergies for adult mammalian locomotion.The Journal of physiology · 2019Article
- Kinematic patterns while walking on a slope at different speeds.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Article
- Velocity-dependent transfer of adaptation in human running as revealed by split-belt treadmill adaptation.Experimental brain research · 2018Article
- Motor module activation sequence and topography in the spinal cord during air-stepping in human: Insights into the traveling wave in spinal locomotor circuits.Physiological reports · 2017Article
- Speed dependency in α-motoneuron activity and locomotor modules in human locomotion: indirect evidence for phylogenetically conserved spinal circuits.Proceedings. Biological sciences · 2017Article
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5 authors.
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Abstract
Coordinated locomotor muscle activity is generated by the spinal central pattern generators (CPGs). Vertebrate studies have demonstrated the following two characteristics of the speed control mechanisms of the spinal CPGs: (i) rostral segment activation is indispensable for achieving high-speed locomotion; and (ii) specific combinations between spinal interneuronal modules and motoneuron (MN) pools are sequentially activated with increasing speed. Here, to investigate whether similar control mechanisms exist in humans, we examined spinal neural activity during varied-speed locomotion by mapping the distribution of MN activity in the spinal cord and extracting locomotor modules, which generate basic MN activation patterns. The MN activation patterns and the locomotor modules were analysed from multi-muscle electromyographic recordings. The reconstructed MN activity patterns were divided into the following three patterns depending on the speed of locomotion: slow walking, fast walking and running. During these three activation patterns, the proportion of the activity in rostral segments to that in caudal segments increased as locomotion speed increased. Additionally, the different MN activation patterns were generated by distinct combinations of locomotor modules. These results are consistent with the speed control mechanisms observed in vertebrates, suggesting phylogenetically conserved spinal mechanisms of neural control of locomotion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.