Evidence map›Paper›PMID 28356420›Full record

ArticleMolecular biology of the cell2017

PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in

Lisa J Edens, Matthew R Dilsaver, Daniel L Levy

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. How the chromatin landscape influences nuclear morphology.Frontiers in cell and developmental biology · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Nuclear growth and import can be uncoupled.Molecular biology of the cell · 2024
    Article
  8. Article
  9. Article
  10. Regulation of organelle size and organization during development.Seminars in cell & developmental biology · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Organelle size scaling over embryonic development.Wiley interdisciplinary reviews. Developmental biology · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Unravelling nuclear size control.Current genetics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lisa J EdensDepartment of Molecular Biology, University of Wyoming, Laramie, WY 82071.
Matthew R DilsaverDepartment of Molecular Biology, University of Wyoming, Laramie, WY 82071.
Daniel L LevyDepartment of Molecular Biology, University of Wyoming, Laramie, WY 82071 dlevy1@uwyo.edu.
University of Wyoming · US

Funding

Integration of Xenopus extract and microfluidics to study organelle size scalingR01GM113028 · NIGMS · UNIVERSITY OF WYOMING · PI LEVY, DANIEL LEON · 2015 to 2019
$1.3M
NIGMS NIH HHS R01 GM113028
6 · The paper itself

Abstract

How nuclear size is regulated is a fundamental cell-biological question with relevance to cancers, which often exhibit enlarged nuclei. We previously reported that conventional protein kinase C (cPKC) contributes to nuclear size reductions that occur during early

Indexed as

Amino Acid SequenceAnimalsCell LineCell NucleusCell Nucleus SizeIntermediate FilamentsInterphaseLaminsLamin Type ALamin Type BMammalsNuclear LaminaNuclear ProteinsPhosphorylationProtein Kinase CSerineLaminsLamin Type ALamin Type BNuclear ProteinsProtein Kinase CSerine

Identifiers

PMID28356420
PMCPMC5426852
OpenAlexW2599961504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.