Evidence map›Paper›PMID 28356406›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2017

Balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension.

Irene Lang, Bernhard C Meyer, Takeshi Ogo, Hiromi Matsubara, Marcin Kurzyna, Hossein-Ardeschir Ghofrani, Eckhard Mayer, Philippe Brenot

Erratum issued Registry-linked trialOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05110066 (Balloon Pulmonary anGiOplasty Versus Pulmonary Endarterectomy in Patients With Chronic ThromboEmbolic Pulmonary Hypertension), which is not on this map. Cited by 100 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 4 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05110066 narecruitingnot on this mapstarted 2024, after this paper: background citation

Balloon Pulmonary anGiOplasty Versus Pulmonary Endarterectomy in Patients With Chronic ThromboEmbolic Pulmonary Hypertension: a Non-inferiority Randomized Trial

TypeinterventionalSponsorUniversity of AarhusRan2024 to 2028Enrolled139ConditionsChronic Thromboembolic Pulmonary HypertensionArmsPulmonary endarterectomy, Balloon pulmonary angioplasty
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 4 syntheses or guidelines pooled it, 238 citations in OpenAlex.

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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Irene LangDept of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria irene.lang@meduniwien.ac.at.
Bernhard C MeyerDept of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Takeshi OgoDivision of Pulmonary Circulation, Dept of Advanced Medicine for Pulmonary Hypertension, National Cerebral and Cardiovascular Center, Suita, Japan.
Hiromi MatsubaraDept of Clinical Science, National Hospital Organization, Okayama Medical Centre, Okayama, Japan.
Marcin KurzynaDept of Pulmonary Circulation and Thromboembolic Diseases, Medical Centre of Postgraduate Education, European Health Centre Otwock, Otwock, Poland.
Hossein-Ardeschir GhofraniUniversities of Giessen and Marburg Lung Center, Giessen, Germany, Member of the German Center for Lung Research (DZL).
Eckhard MayerKerckhoff Heart and Lung Center, Bad Nauheim, Germany.
Philippe BrenotHôpital Marie Lannelongue, Le Plessis-Robinson, France.
Hôpital Marie Lannelongue · FRKerckhoff Klinik · DEMedical University of Vienna · ATMedizinische Hochschule Hannover · DENational Cerebral and Cardiovascular Center · JPNational Hospital Organization · JPUniversities of Giessen and Marburg Lung Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is thought to result from incomplete resolution of pulmonary thromboemboli that undergo organisation into fibrous tissue within pulmonary arterial branches, filling pulmonary arterial lumina with collagenous obstructions. The treatment of choice is pulmonary endarterectomy (PEA) in CTEPH centres, which has low post-operative mortality and good long-term survival. For patients ineligible for PEA or who have recurrent or persistent pulmonary hypertension after surgery, medical treatment with riociguat is beneficial. In addition, percutaneous balloon pulmonary angioplasty (BPA) is an emerging option, and promises haemodynamic and functional benefits for inoperable patients. In contrast to conventional angioplasty, BPA with undersized balloons over guide wires exclusively breaks intraluminal webs and bands, without dissecting medial vessel layers, and repeat sessions are generally required. Observational studies report that BPA improves haemodynamics, symptoms and functional capacity in patients with CTEPH, but controlled trials with long-term follow-up are needed. Complications include haemoptysis, wire injury, vessel dissection, vessel rupture, reperfusion pulmonary oedema, pulmonary parenchymal bleeding and haemorrhagic pleural effusions. This review summarises the available evidence for BPA, patient selection, recent technical refinements and periprocedural imaging, and discusses the potential future role of BPA in the management of CTEPH.

Indexed as

Angioplasty, BalloonAdultAgedChronic DiseaseDiagnostic ImagingFemaleHemodynamicsHumansHypertension, PulmonaryMaleMiddle AgedPredictive Value of TestsPulmonary CirculationPulmonary EmbolismRecovery of FunctionRisk Factors

Identifiers

PMID28356406
PMCPMC9489135
OpenAlexW2602829138

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.