Evidence map›Paper›PMID 28356292›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Responses of distal nephron Na

Gustavo Frindt, Lei Yang, Shinichi Uchida, Alan M Weinstein, Lawrence G Palmer

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Epithelial Na+ Channels, Immune Cells, and Salt.Annual review of physiology · 2025
    Review
  3. Calcineurin inhibitor effects on kidney electrolyte handling and blood pressure: tacrolimus versus voclosporin.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  4. Control of ENaC ubiquitination.American journal of physiology. Renal physiology · 2024
    Article
  5. Review
  6. Influence of proteolytic cleavage of ENaC's γ subunit upon NaAmerican journal of physiology. Renal physiology · 2024
    Article
  7. High dietary KAmerican journal of physiology. Renal physiology · 2023
    Article
  8. Review
  9. Expression of ENaC subunits in epithelia.The Journal of general physiology · 2022
    Article
  10. Directing two-way traffic in the kidney: A tale of two ions.The Journal of general physiology · 2022
    Article
  11. Potassium homeostasis: sensors, mediators, and targets.Pflugers Archiv : European journal of physiology · 2022
    Review
  12. Deletion of Kir5.1 abolishes the effect of high NaAmerican journal of physiology. Renal physiology · 2021
    Article
  13. Cleavage state of γENaC in mouse and rat kidneys.American journal of physiology. Renal physiology · 2021
    Article
  14. Aldosterone-dependent and -independent regulation of NaAmerican journal of physiology. Renal physiology · 2020
    Article
  15. Hyperkalemia: pathophysiology, risk factors and consequences.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019
    Review
  16. Sex difference in kidney electrolyte transport II: impact of KAmerican journal of physiology. Renal physiology · 2019
    Article
  17. Review
  18. Murine epithelial sodium (NaThe Journal of biological chemistry · 2019
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Gustavo FrindtDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Lei YangDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Shinichi UchidaDepartment of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Alan M WeinsteinDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Lawrence G PalmerDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York; lgpalm@med.cornell.edu.
Cornell University · USTokyo Medical and Dental University · JP

Funding

Control of Renal Na and K ExcretionR01DK099284 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI PALMER, LAWRENCE G, WANG, TONG WANG · 2014 to 2017
$2.3M
Defective flow-dependent tubule transport in the pathogenesis of kidney diseaseR01DK117650 · NIDDK · YALE UNIVERSITY · PI WANG, TONG WANG · 2019 to 2022
$1.5M
NIDDK NIH HHS R01 DK099284NIDDK NIH HHS R01 DK117650
6 · The paper itself

Abstract

We assessed effects of acute volume reductions induced by administration of diuretics in rats. Direct block of Na

Indexed as

AmilorideAnimalsDiureticsEpithelial Sodium ChannelsFemaleFurosemideHydrochlorothiazideHyperkalemiaHypovolemiaMaleModels, BiologicalNephronsPhosphorylationPotassiumRats, Sprague-DawleyRenal EliminationAmilorideDiureticsEpithelial Sodium ChannelsFurosemideHydrochlorothiazidePotassiumScnn1g protein, ratSlc12a3 protein, ratSodiumSolute Carrier Family 12, Member 3SpironolactoneamilorideENaCfurosemidehydrochlorothiazidehyperkalemiaNCC

Identifiers

PMID28356292
PMCPMC5538837
OpenAlexW2601059636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.