Observational studyArthritis research & therapy2017
Minimal disease activity and impact of disease in psoriatic arthritis: a Spanish cross-sectional multicenter study.
Observational study in Arthritis research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Guideline
- Trial
- Relationships between psoriatic arthritis composite measures of disease activity with patient-reported outcomes in phase 3 studies of tofacitinib.Arthritis research & therapy · 2021Trial
- Physical fitness and physical activity in psoriatic arthritis: a systematic review.Rheumatology advances in practice · 2025Review
- Sex-specific differences in patients with psoriatic arthritis:a nationwide study from the Chinese Registry of Psoriatic Arthritis (CREPAR IV).Clinical rheumatology · 2024Article
- Article
- Minimal disease activity and associated factors in patients with psoriatic arthritis: cross-sectional study from a single center.Reumatologia · 2024Article
- Moderate-High Disease Activity in Patients with Recent-Onset Psoriatic Arthritis-Multivariable Prediction Model Based on Machine Learning.Journal of clinical medicine · 2023Article
- Outcome measures in psoriatic arthritis: Where next?Musculoskeletal care · 2022Review
- Sex- and gender-related differences in psoriatic arthritis.Nature reviews. Rheumatology · 2022Review
- Telemedicine and psoriatic arthritis: best practices and considerations for dermatologists and rheumatologists.Clinical rheumatology · 2022Review
- Clinical characteristics, disease activity, functional status, and quality of life results of patients with psoriatic arthritis using biological and conventional synthetic disease-modifying antirheumatic drugs.Archives of rheumatology · 2021Article
- A comparison of disease impact according to the cardiometabolic risk profile in psoriatic arthritis.Archives of medical science : AMS · 2021Article
- Measuring Outcomes in Psoriatic Arthritis.Arthritis care & research · 2020Review
- Enthesitis and joint erosions are disease traits associated with cardiovascular risk in psoriatic arthritis.Clinical rheumatology · 2020Observational
- Results of a global, patient-based survey assessing the impact of psoriatic arthritis discussed in the context of the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire.Health and quality of life outcomes · 2020Article
- Psoriatic arthritis impact of disease questionnaire: validity, reliability and its clinical potential.Rheumatology international · 2020Observational
- Disease features associated with a low disease impact in patients with psoriatic arthritis: results of a cross-sectional multicenter study.Arthritis research & therapy · 2020Observational
- Treat-to-target in PsA: methods and necessity.RMD open · 2020Review
- Analysis by Age Group of Disease Outcomes in Patients with Psoriatic Arthritis: A Cross-Sectional Multicentre Study.Drugs & aging · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with psoriatic arthritis (PsA) experience functional impairment and reduced quality of life, and thus patient global assessment in PsA is explained mainly by the physical, but also by the psychological, aspect of the disease. To assess the prevalence of minimal disease activity (MDA) in Spanish patients with PsA, we examined their characteristics and the association between MDA and the impact of the disease as assessed by the PsA Impact of Disease (PsAID) questionnaire.
methodsA cross-sectional multicenter study was carried out in patients who fulfilled the Classification for Psoriatic Arthritis (CASPAR) criteria with at least 1 year of disease duration, and who were treated with biological or conventional synthetic (cs) disease-modifying anti-rheumatic drugs (DMARDs) according to routine clinical practice in Spain. Patients were considered in MDA if they met at least 5/7 of the MDA criteria. The association between MDA and the recently developed PsAID questionnaire was also recorded.
resultsOf 227 patients included, 133 (58.6%) were in the MDA state (52% with antitumor necrosis factor (anti-TNF)α monotherapy, 24% with csDMARD monotherapy, and 24% with anti-TNFα in combination with csDMARD). Using multivariate logistic regression analysis, male gender (odds ratio (OR) 2.74, p = 0.001), a sedentary lifestyle (OR 3.13, p = 0.002), familial history of PsA (OR 0.38, p = 0.036), C-reactive protein (CRP) level (OR 0.92, p = 0.010), and use of corticoids (OR 0.33, p = 0.007) were considered features related to MDA. MDA patients had a significantly lower impact of the disease according to PsAID (mean total score (SD): MDA 3.3 (3.1) vs. non-MDA 7.1 (5.2); p < 0.001).
conclusionsNearly 60% of Spanish PsA patients achieve MDA in routine clinical practice. MDA remains one of the most useful therapeutic targets for PsA since patients who reached this state also had a significantly lower impact of disease according to PsAID.
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