ArticleBMC psychiatry2017
Parental separation in childhood as a risk factor for depression in adulthood: a community-based study of adolescents screened for depression and followed up after 15 years.
Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 61 citations in OpenAlex.
- Mental Health Outcomes of Foster and Adopted Individuals with Adverse Childhood Experiences: A Validation of Known Risks Using EHR Data.medRxiv : the preprint server for health sciences · 2026Article
- Association between perinatal depressive symptoms and parental cohabitation status in a Nordic high-income country.PloS one · 2026Article
- Article
- The effect of parental marital status on non-suicidal self-injurious behavior among middle school students in rural western China: a multicenter cross-sectional study based on propensity score matching method.Frontiers in psychiatry · 2025Article
- Atypical Brain Aging and Its Association With Working Memory Performance in Major Depressive Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Parental absence as an adverse childhood experience among young adults in sub-Saharan Africa.Child abuse & neglect · 2024Article
- The impact of comorbid premenstrual syndrome or premenstrual dysphoric disorder on the clinical characteristics of bipolar disorder among Han Chinese women.Archives of women's mental health · 2024Article
- Depressive symptoms among adolescents in six sub-Saharan African countries: A pooled analysis of associated factors.Preventive medicine reports · 2023Article
- Mental health status and stressful life events among postgraduate nursing students in Cyprus: a cross-sectional descriptive correlational study.BMC nursing · 2023Article
- [Prevention of mental health disorders in primary care: Children of single-parent families. Pregnancy in adolescence].Atencion primaria · 2022Article
- Childhood adversities and mental health problems: A systematic review.Journal of public health research · 2022Article
- The mediating pathways between parental separation in childhood and offspring hypertension at midlife.Scientific reports · 2022Article
- Effects of somatic treatments on suicidal ideation and completed suicides.Brain and behavior · 2021Review
- Association between parental divorce and mental health outcomes among Lebanese adolescents: results of a national study.BMC pediatrics · 2021Article
- Alcohol Use Disorder and Risk of Suicide in a Swedish Population-Based Cohort.The American journal of psychiatry · 2020Article
- Parent-youth conflict as a predictor of depression in adulthood: a 15-year follow-up of a community-based cohort.European child & adolescent psychiatry · 2020Article
- Uppsala Longitudinal Adolescent Depression Study (ULADS).BMJ open · 2019Article
- Relationship Between Adverse Childhood Experience Survey Items and Psychiatric Disorders.The Permanente journal · 2018Article
- Association between Adverse Childhood Experiences and Internalizing Symptoms in Adults at a Wellness Centre in India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarlier research has investigated the association between parental separation and long-term health outcomes among offspring, but few studies have assessed the potentially moderating role of mental health status in adolescence. The aim of this study was to analyze whether parental separation in childhood predicts depression in adulthood and whether the pattern differs between individuals with and without earlier depression.
methodsA community-based sample of individuals with adolescent depression in 1991-93 and matched non-depressed peers were followed up using a structured diagnostic interview after 15 years. The participation rate was 65% (depressed n = 227; non-depressed controls n = 155). Information on parental separation and conditions in childhood and adolescence was collected at baseline. The outcome was depression between the ages 19-31 years; information on depression was collected at the follow-up diagnostic interview. The statistical method used was binary logistic regression.
resultsOur analyses showed that depressed adolescents with separated parents had an excess risk of recurrence of depression in adulthood, compared with depressed adolescents with non-separated parents. In addition, among adolescents with depression, parental separation was associated with an increased risk of a switch to bipolar disorder in adulthood. Among the matched non-depressed peers, no associations between parental separation and adult depression or bipolar disorder were found.
conclusionsParental separation may have long-lasting health consequences for vulnerable individuals who suffer from mental illness already in adolescence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.