Evidence map›Paper›PMID 28356072›Full record

ArticleBMC genomics2017

Comparative and functional genomics of the Lactococcus lactis taxon; insights into evolution and niche adaptation.

Philip Kelleher, Francesca Bottacini, Jennifer Mahony, Kieran N Kilcawley, Douwe van Sinderen

Abstract read
In one paragraph

Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Menaquinone biosynthesis inEngineering microbiology · 2026
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  7. Anti-Inflammatory Function Analysis ofBiotech (Basel (Switzerland)) · 2025
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  8. Genomic Insights into ProbioticMicroorganisms · 2025
    Article
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  11. Article
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  14. Defense systems and horizontal gene transfer in bacteria.bioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Lactococcus lactis, a bacterium with probiotic functions and pathogenicity.World journal of microbiology & biotechnology · 2023
    Review
  18. Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip KelleherSchool of Microbiology, University College Cork, Cork, Ireland.ORCID 0000-0003-3423-7930
Francesca BottaciniAlimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.
Jennifer MahonySchool of Microbiology, University College Cork, Cork, Ireland.
Kieran N KilcawleyDepartment of Food Biosciences, Teagasc Food Research Centre, Moorepark, Cork, Ireland.
Douwe van SinderenSchool of Microbiology, University College Cork, Cork, Ireland. d.vansinderen@ucc.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLactococcus lactis is among the most widely studied lactic acid bacterial species due to its long history of safe use and economic importance to the dairy industry, where it is exploited as a starter culture in cheese production.

resultsIn the current study, we report on the complete sequencing of 16 L. lactis subsp. lactis and L. lactis subsp. cremoris genomes. The chromosomal features of these 16 L. lactis strains in conjunction with 14 completely sequenced, publicly available lactococcal chromosomes were assessed with particular emphasis on discerning the L. lactis subspecies division, evolution and niche adaptation. The deduced pan-genome of L. lactis was found to be closed, indicating that the representative data sets employed for this analysis are sufficient to fully describe the genetic diversity of the taxon.

conclusionsNiche adaptation appears to play a significant role in governing the genetic content of each L. lactis subspecies, while (differential) genome decay and redundancy in the dairy niche is also highlighted.

Indexed as

Evolution, MolecularGenome, BacterialAmino Acid Transport SystemsCarbohydrate MetabolismCarrier ProteinsCluster AnalysisComparative Genomic HybridizationLactococcus lactisLipid MetabolismPhylogenyRNA, Ribosomal, 16SAmino Acid Transport SystemsCarrier Proteinslipid transfer proteinRNA, Ribosomal, 16SGenomicsLactococcus lactisNiche adaptationPan-genomeSMRT sequencing

Identifiers

PMID28356072
PMCPMC5372332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.