Evidence map›Paper›PMID 28355990›Full record

ArticleThe journal of spinal cord medicine2017

Active elbow flexion is possible in C4 quadriplegia using hybrid assistive limb (HAL®) technology: A case study.

Yukiyo Shimizu, Hideki Kadone, Shigeki Kubota, Akira Ikumi, Tetsuya Abe, Aiki Marushima, Tomoyuki Ueno, Ayumu Endo, Hiroaki Kawamoto, Kousaku Saotome and 5 more

Abstract readCase Reports
In one paragraph

Article in The journal of spinal cord medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Yukiyo Shimizua Department of Rehabilitation Medicine , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.ORCID 0000-0001-7491-4516
Hideki Kadoneb Center for Innovative Medicine and Engineering , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.
Shigeki Kubotac Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.
Akira Ikumid Department of Orthopaedic Surgery, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.ORCID 0000-0001-6034-1593
Tetsuya Abed Department of Orthopaedic Surgery, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.
Aiki Marushimae Department of Neurosurgery, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.
Tomoyuki Uenoa Department of Rehabilitation Medicine , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.
Ayumu Endoa Department of Rehabilitation Medicine , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.
Hiroaki Kawamotof Faculty of Systems and Information Engineering , University of Tsukuba , Tsukuba, Ibaraki 305-8573 , Japan.
Kousaku Saotomeb Center for Innovative Medicine and Engineering , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.
Akira Matsushitag Department of Neurosurgery , Ibaraki Prefectural University Hospital of Health Sciences , Inashiki-gun, Ibaraki 300-0331 , Japan.ORCID 0000-0003-2335-674X
Akira Matsumurae Department of Neurosurgery, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.
Yoshiyuki Sankaif Faculty of Systems and Information Engineering , University of Tsukuba , Tsukuba, Ibaraki 305-8573 , Japan.
Yasushi Hadaa Department of Rehabilitation Medicine , University of Tsukuba Hospital , Tsukuba, Ibaraki 305-8576 , Japan.
Masashi Yamazakid Department of Orthopaedic Surgery, Faculty of Medicine , University of Tsukuba , Tsukuba, Ibaraki 305-8575 , Japan.
University of Tsukuba · JPUniversity of Tsukuba Hospital · JPIbaraki Prefectural University of Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextPatients with complete quadriplegia after high cervical spinal cord injury are fully dependent with activities of daily living. Assistive technology can improve their quality of life. We examined the use of a hybrid assistive limb for single joints (HAL-SJ) in a 19-year-old man with complete C4 quadriplegia due to chronic spinal cord injury to restore function of active elbow flexion. This is the first report on the use of the HAL-SJ in a patient with spinal cord injury.

findingsThe HAL-SJ intervention for each elbow was administered in 10 sessions. Clinical assessment using surface EMG was conducted to evaluate muscle activity of the trapezius, biceps brachii, infraspinatus, and triceps brachii muscle before, and during the 2nd, 3rd, 6th, and 9th interventions. Surface electromyography (EMG) before intervention showed no contraction in the upper arms, but in the bilateral trapezius. The HAL-SJ used motion intention from the right trapezius for activation. After the 6th and 7th session, respectively, biceps EMG showed that voluntary contraction and right elbow flexion could be performed by motion intention from the right biceps. After the 10th session, voluntary bicep contraction was possible. HAL-SJ treatment on the left elbow was performed using the same protocol with a similar outcome. After completing treatment on both upper extremities, both biceps contracted voluntarily, and he could operate a standard wheelchair for a short distance independently.

conclusionHAL-SJ intervention is feasible and effective in restoring elbow flexor function in a patient with C4 chronic spinal cord injury and complete quadriplegia.

Indexed as

Muscle ContractionElbowHumansMaleMotion Therapy, Continuous PassiveMuscle, SkeletalNeurological RehabilitationQuadriplegiaYoung AdultActive elbow flexionComplete quadriplegiaHybrid assistive limb for single jointSpinal cord injurySurface electromyography

Identifiers

PMID28355990
PMCPMC5537963
OpenAlexW2600220984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.