Evidence map›Paper›PMID 28355836›Full record

ArticleThe Behavioral and brain sciences2016

GANEing traction: The broad applicability of NE hotspots to diverse cognitive and arousal phenomena.

Mara Mather, David Clewett, Michiko Sakaki, Carolyn W Harley

Abstract read
In one paragraph

Article in The Behavioral and brain sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Potential of Cognitive-Inspired Neural Network Modeling Framework for Computer Vision.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Locus coeruleus input-modulated reactivation of dentate gyrus opioid-withdrawal engrams promotes extinction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  9. Review
  10. Aversive learning strengthens episodic memory in both adolescents and adults.Learning & memory (Cold Spring Harbor, N.Y.) · 2019
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mara MatherDavis School of Gerontology,University of Southern California,Los Angeles,CA 90089-0191mara.mather@usc.edumatherlab.com.
David ClewettNeuroscience Graduate Program,University of Southern California,Los Angeles,CA 90089-2520clewett@usc.eduhttp://dornsifecms.usc.edu/david-clewett-neuroscience/.
Michiko SakakiSchool of Psychology and Clinical Language Sciences,University of Reading,Reading RGX 7BE,United Kingdomm.sakaki@reading.ac.ukhttp://www.reading.ac.uk/psychology/about/staff/m-sakaki.aspx.
Carolyn W HarleyProfessor Emeritus,Memorial University of Newfoundland,St. John's,NL A1C 5S7,Canadacharley@play.psych.mun.cahttps://www.mun.ca/psychology/bio/harley.php.

Funding

The Impact of Emotional Regulation on Cognition in AgingR01AG025340 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MATHER, MARA · 2004 to 2021
$7.9M
NIA NIH HHS R01 AG025340
6 · The paper itself

Abstract

The GANE (glutamate amplifies noradrenergic effects) model proposes that local glutamate-norepinephrine interactions enable "winner-take-more" effects in perception and memory under arousal. A diverse range of commentaries addressed both the nature of this "hotspot" feedback mechanism and its implications in a variety of psychological domains, inspiring exciting avenues for future research.

Indexed as

ArousalMemoryCognitionHumansNorepinephrineNorepinephrine

Identifiers

PMID28355836
PMCPMC5780186

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.