Evidence map›Paper›PMID 28353652›Full record

ArticleNutrients2017

Inhibitory Effect of Lychee Seed Saponins on Apoptosis Induced by Aβ

Xiuling Wang, Hong Zhang, Jian Liu, Rong Chen, Yong Tang, Haixia Chen, Li Gu, Mao Li, Shousong Cao, Dalian Qin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xiuling WangDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. wangxiulingbest@gmail.com.
Hong ZhangDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. m18989131787_1@163.com.
Jian LiuDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. belkn@sohu.com.
Rong ChenDepartment of Human Anatomy, School of Preclinical Medicine, Southwest Medical University, Luzhou 646000, China.
Yong TangDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. tangy1989@yeah.net.
Haixia ChenDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. dna0805001@163.com.
Li GuDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. tristan19810102@icloud.com.
Mao LiDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. batilimao@163.com.
Shousong CaoDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. shousongc@gmail.com.
Dalian QinDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. dalianqin@swmu.edu.cn.
Jianming WuDepartment of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, China. jianmingwu@swmu.edu.cn.
Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal apoptosis plays a critical role in the pathogenesis of Alzheimer's disease (AD). Previous studies have shown that lychee seed saponins (LSS), isolated and extracted from traditional Chinese medicine lychee seeds, possess many beneficial activities including anti-oxidation, anti-diabetes, anti-AD, etc. In the present study, we established an in vitro neuronal apoptotic model of PC12 cells induced by Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisCell SurvivalLitchiMembrane Potential, MitochondrialMitochondriaNeuronsNeuroprotective AgentsNF-kappa BPC12 CellsPeptide FragmentsPhytotherapyPlant ExtractsProto-Oncogene Proteins c-bcl-2Amyloid beta-Peptidesamyloid beta-protein (25-35)Neuroprotective AgentsNF-kappa BPeptide FragmentsPlant ExtractsProto-Oncogene Proteins c-bcl-2SaponinsAlzheimer’s diseaseapoptosisAβ25-35lychee seed saponinsNF-κBPC12 cells

Identifiers

PMID28353652
PMCPMC5409676
OpenAlexW2603163475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.