Evidence map›Paper›PMID 28353212›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Stress-induced alteration of left ventricular eccentricity: An additional marker of multivessel CAD.

Alessia Gimelli, Riccardo Liga, Assuero Giorgetti, Mirta Casagranda, Paolo Marzullo

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Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Incremental value of left ventricular shape parameters measured by gated SPECT MPI in predicting the super-response to CRT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Quantitation of Poststress Change in Ventricular Morphology Improves Risk Stratification.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  8. Is left ventricular systolic index the new kid in the block?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  9. Assessing LV remodeling in nuclear cardiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alessia GimelliFondazione Toscana G. Monasterio, Pisa, Italy.
Riccardo LigaCardio-Thoracic and Vascular Department, University Hospital of Pisa, Via Paradisa 2, 56100, Pisa, Italy. riccardo.liga@gmail.com.
Assuero GiorgettiFondazione Toscana G. Monasterio, Pisa, Italy.
Mirta CasagrandaFondazione Toscana G. Monasterio, Pisa, Italy.
Paolo MarzulloFondazione Toscana G. Monasterio, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbnormal left ventricular (LV) eccentricity index (EI) is a marker of adverse cardiac remodeling. However, the interaction between stress-induced alterations of EI and major cardiac parameters has not been explored. We sought to evaluate the relationship between LV EI and coronary artery disease (CAD) burden in patients submitted to myocardial perfusion imaging (MPI). METHODS AND

resultsThree-hundred and forty-three patients underwent MPI and coronary angiography. LV ejection fraction (EF) and EI were computed from gated stress images as measures of stress-induced functional impairment. One-hundred and thirty-six (40%), 122 (35%), and 85 (25%) patients had normal coronary arteries, single-vessel CAD, and multivessel CAD, respectively. Post-stress EI was lower in patients with multivessel CAD than in those with normal coronary arteries and single-vessel CAD (P = 0.001). This relationship was confirmed only in patients undergoing exercise stress test, where a lower post-stress EI predicted the presence of multivessel CAD (P = 0.039).

conclusionsPost-stress alterations of LV EI on MPI may unmask the presence of multivessel CAD.

Indexed as

Coronary AngiographyMyocardial Perfusion ImagingAgedAlgorithmsCoronary Artery DiseaseCoronary VesselsExercise TestFemaleHeart VentriclesHumansMaleMiddle AgedPerfusionStroke VolumeTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftCZTeccentricity indexejection fractiongated SPECTLeft ventricular remodeling

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.