Evidence map›Paper›PMID 28353064›Full record

ArticleNeuroradiology2017

Radiological imaging features of the basal ganglia that may predict progression to hemicraniectomy in large territory middle cerebral artery infarct.

Asim Z Mian, David Edasery, Osamu Sakai, M Mustafa Qureshi, James Holsapple, Thanh Nguyen

Abstract read
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In one paragraph

Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Asim Z MianDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, FGH Building, 3, Boston, MA 02118, USA. asim.mian@bmc.org.
David EdaseryDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, FGH Building, 3, Boston, MA 02118, USA.
Osamu SakaiDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, FGH Building, 3, Boston, MA 02118, USA.
M Mustafa QureshiDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, FGH Building, 3, Boston, MA 02118, USA.
James HolsappleDepartment of Neurosurgery, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Thanh NguyenDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Boston University · USBoston Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePredicting which patients are at risk for hemicraniectomy can be helpful for triage and can help preserve neurologic function if detected early. We evaluated basal ganglia imaging predictors for early hemicraniectomy in patients with large territory anterior circulation infarct.

methodsThis retrospective study evaluated patients with ischemic infarct admitted from January 2005 to July 2011. Patients with malignant cerebral edema refractory to medical therapy or with herniating signs such as depressed level of consciousness, anisocoria, and contralateral leg weakness were triaged to hemicraniectomy. Admission images were reviewed for presence of caudate, lentiform nucleus (putamen and globus pallidus), or basal ganglia (caudate + lentiform nucleus) infarction.

resultsThirty-one patients with large territory MCA infarct, 10 (32%), underwent hemicraniectomy. Infarction of the caudate nucleus (9/10 vs 6/21, p = 0.002) or basal ganglia (5/10 vs 2/21, p = 0.02) predicted progression to hemicraniectomy. Infarction of the lentiform nucleus only did not predict progression to hemicraniectomy. Sensitivity for patients who did and did not have hemicraniectomy were 50% (5/10) and 90.5% (19/21). For caudate nucleus and caudate plus lentiform nucleus infarcts, the crude- and age-adjusted odds of progression to hemicraniectomy were 9.5 (1.4-64.3) and 6.6 (0.78-55.4), respectively.

conclusionInfarction of the caudate nucleus or basal ganglia correlated with patients progressing to hemicraniectomy. Infarction of the lentiform nucleus alone did not.

Indexed as

Basal GangliaBrain EdemaCraniotomyFemaleHumansInfarction, Middle Cerebral ArteryMaleMiddle AgedNeuroimagingRetrospective StudiesBasal gangliaCTHemicraniectomyMRIStroke

Identifiers

PMID28353064
OpenAlexW2597697165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.