Evidence map›Paper›PMID 28352983›Full record

ArticleAIDS and behavior2018

An update on the Barriers to Adherence and a Definition of Self-Report Non-adherence Given Advancements in Antiretroviral Therapy (ART).

John A Sauceda, Torsten B Neilands, Mallory O Johnson, Parya Saberi

Abstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. The Brief Human Immunodeficiency Virus (HIV) Index: A Rapid 3-Item Scale to Measure Engagement in HIV Care.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John A SaucedaCenter for AIDS Prevention Studies, Department of Medicine, University of California - San Francisco, San Francisco, CA, USA. john.sauceda@ucsf.edu.
Torsten B NeilandsCenter for AIDS Prevention Studies, Department of Medicine, University of California - San Francisco, San Francisco, CA, USA.
Mallory O JohnsonCenter for AIDS Prevention Studies, Department of Medicine, University of California - San Francisco, San Francisco, CA, USA.
Parya SaberiCenter for AIDS Prevention Studies, Department of Medicine, University of California - San Francisco, San Francisco, CA, USA.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
John A. Sauceda Research Supplement to Promote Diversity in Health-Related Research to M.O. Johnson's Parent Grant R01 MH102198R01MH102198 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTOPOULOS, KATERINA A, JOHNSON, MALLORY O · 2013 to 2017
$3.5M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Technology-based adaptive treatment strategies for antiretroviral adherenceK23MH097649 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SABERI, PARYA · 2012 to 2016
$890k
NIAID NIH HHS P30 AI027763NIDA NIH HHS K24 DA037034NIMH NIH HHS K23 MH097649NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH102198NIMH NIH HHS T32 MH019105
6 · The paper itself

Abstract

Relying on the most frequently reported barriers to adherence and convenient definitions of non-adherence may lead to less valid results. We used a dominance analysis (a regression-based approach) to identify the most important barriers to adherence based on effect size using data collected through an online survey. The survey included the Adherence Barrier Questionnaire, self-reported non-adherence defined as a 4-day treatment interruption, and HIV clinical outcomes. The sample (N = 1217) was largely male, gay identified, and White. Nearly 1 in 3 participants reported "simply forgot" as a barrier; however, in a dominance analysis, it yielded a small effect size it its association with a 4-day treatment interruption. Further, dominance analyses stratified by race/ethnicity and age suggested that not all barriers impact all groups equally. The most frequently reported barriers to adherence were not the most important, and interventions should focus on barriers more strongly linked to clinical outcomes.

Indexed as

Attitude to HealthHomosexuality, MaleAdultAnti-HIV AgentsBlack or African AmericanHispanic or LatinoHIV InfectionsHumansMaleMedication AdherenceMiddle AgedPain ManagementSelf ReportSocial SupportStress, PsychologicalSurveys and QuestionnairesAnti-HIV AgentsAdherenceAdherence barriersAntiretroviral therapyDominance analysisRelative importance

Identifiers

PMID28352983
PMCPMC5617751

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.