Evidence map›Paper›PMID 28352834›Full record

ArticleOpen medicine (Warsaw, Poland)2016

Preoperative high-intensity training in frail old patients undergoing pulmonary resection for NSCLC.

Rosario Salvi, Ilernando Meoli, Antonio Cennamo, Fabio Perrotta, Francesco Saverio Cerqua, Raffaele Montesano, Carlo Curcio, Francesco Lassandro, Francesco Stefanelli, Edoardo Grella and 3 more

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Impact of preoperative respiratory training on early postoperative recovery in patients undergoing lung cancer surgery: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  2. Article
  3. Food, Nutrition, Physical Activity and Microbiota: Which Impact on Lung Cancer?International journal of environmental research and public health · 2021
    Review
  4. Review
  5. Review
  6. Review
  7. Frailty and anesthesia - risks during and post-surgery.Local and regional anesthesia · 2018
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Rosario Salvi *Unit of Thoracic Surgery, A.O. Dei Colli - Monaldi Hospital, Naples, Italy.
Ilernando Meoli *Unit of Pneumology, A.O. Dei Colli - Monaldi Hospital, Naples, Italy.
Antonio CennamoDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Fabio PerrottaDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Francesco Saverio CerquaDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Raffaele MontesanoDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Carlo CurcioUnit of Thoracic Surgery, A.O. Dei Colli - Monaldi Hospital, Naples, Italy.
Francesco LassandroUnit of Radiology, A.O. Dei Colli - Monaldi Hospital, Naples, Italy.
Francesco StefanelliUnit of Pneumology, A.O. Dei Colli - Monaldi Hospital, Naples, Italy.
Edoardo GrellaDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Domenico TafuriDepartment of Sport Sciences and Wellness, University of Naples "Parthenope", Naples, Italy.
Gennaro MazzarellaDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples, A.O. Dei Colli - Monaldi Hospital, Via Leonardo Bianchi, 80131, Naples, Italy.
Andrea BiancoDepartment of Cardiothoracic and Respiratory Sciences, Second University of Naples/Hosp. Monaldi, Piazza Miraglia, 2, 80138 Naples, Italy Phone:+390815665228, , E-mail: andrea_bianco_1962@yahoo.it.
Ospedale Monaldi · ITUniversity of Campania "Luigi Vanvitelli" · ITParthenope University of Naples · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thoracic surgery remains the better therapeutic option for non-small cell lung cancer patients that are diagnosed in early stage disease. Preoperative lung function assessment includes respiratory function tests (RFT) and cardio-pulmonary exercise testing (CPET). Vo2 peak, FEV1 and DLCO as well as recognition of performance status, presence of co-morbidities, frailty indexes, and age predict the potential impact of surgical resection on patient health status and survival risk. In this study we have retrospectively assessed the benefit of a high-intensity preoperative pulmonary rehabilitation program (PRP) in 14 patients with underlying lung function impairment prior to surgery. Amongst these, three patients candidate to surgical resection exhibited severe functional impairment associated with high score of frailty according CHS and SOF index, resulting in a substantial mortality risk. Our observations indicate that PRP appear to reduce the mortality and morbidity risk in frail patients with concurrent lung function impairment undergoing thoracic surgery. PRP produced improvement of VO2 peak degree and pulmonary function resulting in reduced postoperative complications in high-risk patients from our cases. Our results indicate that a preoperative training program may improve postoperative clinical outcomes in fraillung cancer patients with impaired lung function prior to surgical resection.

Indexed as

AgingFrail patientsNon-small cell lung cancerPulmonary rehabilitation programRespiratory function testsThoracic Surgery

Identifiers

PMID28352834
PMCPMC5329866
OpenAlexW2550454764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.