ArticleOpen medicine (Warsaw, Poland)2016
Role of FDG-PET scan in staging of pulmonary epithelioid hemangioendothelioma.
Article in Open medicine (Warsaw, Poland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Primary pulmonary epithelioid hemangioendothelioma.BMJ case reports · 2023Article
- Case report: Rare epithelioid hemangioendothelioma occurs in both main bronchus and lung.Frontiers in medicine · 2022Article
- Epithelioid hemangioendothelioma: evaluation byAmerican journal of nuclear medicine and molecular imaging · 2021Article
- Effective combined therapy for pulmonary epithelioid hemangioendothelioma: A case report.World journal of clinical cases · 2020Article
- [Research Progress of Pulmonary Epithelioid Hemangioendothelioma].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2019Review
- Apatinib for the treatment of pulmonary epithelioid hemangioendothelioma: A case report and literature review.Medicine · 2017Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this report we describe a case of pulmonary epithelioid hemangioendothelioma (PEH) in a young woman. The neoplasm manifested with dry cough, chest pain, finger clubbing, and multiple bilateral pulmonary nodules on chest x-ray and computed tomographic (CT) scan. She underwent thoracoscopy, and the histological features of the lung biopsies were initially interpreted as consistent with a not-well-defined interstitial lung disease. Our patient was clinically and radiologically stable over a period of four years, after which the disease progressed to involve not only the lung but also mediastinal lymph nodes, liver and bone. Fiberoptic bronchoscopy showed subtotal occlusion of the right middle and lower lobe bronchi. The histologic examination of bronchial biopsies revealed a poorly differentiated neoplasm immunohistochemically positive for vimentin and vascular markers CD31, CD34 and Factor VIII. A diagnosis of malignant hemangioendothelioma was made. Positron emission tomography (PET) is more sensitive than CT scan and bone scintigraphy in detecting PEH metastases. Furthermore, 18-fluorodeoxyglucose (FDG) uptake seems to be related to the grade of malignancy of PEH lesions. Therefore, we suggest that FDG-PET should be included in the staging system and follow-up of PEH.
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