Evidence map›Paper›PMID 28352706›Full record

ArticleOpen medicine (Warsaw, Poland)2015

Profile of adult acute cholinesterase inhibitors substances poisoning - a 30 years analysis.

Eugen N Gazzi, Victorita Sorodoc, Irina M Jaba, Catalina Lionte, Cristina Bologa, Catalina E Lupusoru, Raoul Lupusoru, Laurentiu Sorodoc, Ovidiu Petris

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eugen N Gazzi"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Victorita Sorodoc"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania, Tel: +40728040582.
Irina M JabaPharmacology - Toxicology Department, Faculty of Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Catalina Lionte"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Cristina Bologa"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Catalina E LupusoruPharmacology - Toxicology Department, Faculty of Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Raoul LupusoruPhysiopathology Department, Faculty of Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Laurentiu Sorodoc"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Ovidiu Petris"Sf. Spiridon" Emergency Clinic Hospital, Internal Medicine and Toxicology Department, School of Medicine "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to assess the pattern and outcome of acute cholinesterase inhibitors substances (CIS) poisoning cases, in a cohort from a regional tertiary care hospital.

methodscases admitted in the Toxicology Clinic of "Sf. Spiridon" Emergency Clinic Hospital Iasi, Romania between 1983 and 2013 were studied.

resultsa total number of 606 patients were included. The reason for exposures was intentional in 70% of cases and the commonest route of poisoning was oral in 92.2%. The highest percent of cases was females (56.4), the age group 20-29 (25.4%) and the majority (66.7%) coming from rural areas, 28.2% being agricultural workers. 36.6% of cases were severe clinical forms. Overall mortality rates were 3.8%, more than half of the death patients (65.2%) had concomitant alcohol intake. It was a significant statistical association between decrease level of serum cholinesterase on admittance and severe forms (p 0.000) and between survival and deaths groups (p 0.000). The pattern of poisoning described by our retrospective study suggests that CIS poisoning are mainly preventable. The main effective goals for prevention are restriction in free accessibility to toxic pesticides, together with sustained efforts in education concerning the life-threatening danger of pesticide poisoning.

Indexed as

Epidemiologypesticidetoxicity

Identifiers

PMID28352706
PMCPMC5152987

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.