Evidence map›Paper›PMID 28352642›Full record

ArticleJournal of immunology research2017

The Expression of IL-6, TNF-

Jingtong Zheng, Yue Shi, Lingxin Xiong, Weijie Zhang, Ying Li, Peter G Gibson, Jodie L Simpson, Chao Zhang, Junying Lu, Jingying Sai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Viral Infection and Airway Epithelial Immunity in Asthma.International journal of molecular sciences · 2022
    Review
  10. Review
  11. Article
  12. Acute Effects of Heated Tobacco Product (IQOS) Aerosol Inhalation on Lung Tissue Damage and Inflammatory Changes in the Lungs.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  13. Does Interleukin-6 Bridge SARS-CoV-2 With Virus-Associated Cancers?Journal of immunotherapy and precision oncology · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Jingtong ZhengDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China.
Yue ShiDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China.
Lingxin XiongDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China; School of Pharmaceutical Sciences, Jilin University, Jilin, China.ORCID 0000-0002-0160-7467
Weijie ZhangDepartment of Respiratory Disease, Jilin Provincial People's Hospital, Changchun, China.
Ying LiDepartment of Disease Control and Prevention, Beijing Shunyi District Center, Beijing, China.
Peter G GibsonDepartment of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia.
Jodie L SimpsonDepartment of Respiratory and Sleep Medicine, University of Newcastle, New Lambton, NSW, Australia.ORCID 0000-0001-5299-4236
Chao ZhangDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China.
Junying LuDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China; Department of Intensive Care Unit, First Hospital of Jilin University, Changchun 130021, China.
Jingying SaiDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China; Department of Clinical Laboratory, The Second Hospital of Jilin University, Changchun 130021, China.
Guoqiang WangDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China.
Fang WangDepartments of Pathogenic Biology, College of Basic Medical Sciences, Jilin university, Changchun, China.ORCID 0000-0003-0871-3454
Jilin University · CNBeijing Center for Disease Prevention and Control · CNJohn Hunter Hospital · AUPeople 's Hospital of Jilin Province · CNSecond Affiliated Hospital of Jilin University · CNUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infection is a common trigger for acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of this study is to investigate the expression of cytokines in AECOPD. Patients with AECOPD requiring hospitalization were recruited. Meanwhile healthy volunteers of similar age that accepted routine check-ups and showed no clinical symptoms of inflammatory diseases were also recruited. Induced sputum and serum were collected. Induced sputum of participants was processed and tested for thirteen viruses and bacteria. Forty cytokines were assayed in serum using the Quantibody Human Inflammation Array 3 (Ray Biotech, Inc.). The most common virus detected in virus positive AECOPD (VP) was influenza A (16%). No virus was found in controls. Circulating levels of IL-6, TNF-

Indexed as

AgedAged, 80 and overAnimalsBiomarkersChemokine CCL2Disease ProgressionFemaleGene Expression ProfilingHumansInterleukin-6MacrophagesMaleMiddle AgedPhenotypePulmonary Disease, Chronic ObstructiveRespiratory Tract InfectionsBiomarkersChemokine CCL2Interleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID28352642
PMCPMC5352889
OpenAlexW2592181495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.