Evidence map›Paper›PMID 28352620›Full record

ArticleProstate international2017

Indications for a second prostate biopsy in patients suspected with prostate cancer after an initial negative prostate biopsy.

Kwang Suk Lee, Kyo Chul Koo, Kang Su Cho, Seung Hwan Lee, Woong Kyu Han, Young Deuk Choi, Sung Joon Hong, Sang Un Park, Suk Young Lee, Woo Jin Ko and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Prostate international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kwang Suk LeeDepartment of Urology, Gangnam Severance hospital, Yonsei University College of Medicine, Seoul, South Korea.
Kyo Chul KooDepartment of Urology, Gangnam Severance hospital, Yonsei University College of Medicine, Seoul, South Korea.
Kang Su ChoDepartment of Urology, Gangnam Severance hospital, Yonsei University College of Medicine, Seoul, South Korea.
Seung Hwan LeeDepartment of Urology, Sinchon Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Woong Kyu HanDepartment of Urology, Sinchon Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Young Deuk ChoiDepartment of Urology, Sinchon Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Sung Joon HongDepartment of Urology, Sinchon Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Sang Un ParkDepartment of Urology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Suk Young LeeDepartment of Urology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Woo Jin KoDepartment of Urology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Young Sig KimDepartment of Urology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Byung Ha ChungDepartment of Urology, Gangnam Severance hospital, Yonsei University College of Medicine, Seoul, South Korea.
Yonsei University · KRNational Health Insurance Service Ilsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aimed to evaluate the indications for a second prostate biopsy in patients suspected with prostate cancer after an initial negative prostate biopsy.

methodsThe present study included 421 patients who underwent repeat prostate biopsy between January 2007 and December 2015 at three hospitals. Clinicopathological data, including patient age, body mass index, history of prostate biopsy, prostate volume, prostate-specific antigen (PSA) level, PSA density, PSA velocity, and PSA fluctuation patterns, were analyzed. The patients were stratified into two groups based on the first PSA pattern (increase/decrease) within 1 year after the initial negative prostate biopsy.

resultsProstate cancer was detected in 100 (23.8%) of the 421 patients at the second prostate biopsy. In patients with a PSA decrease at the first follow-up, prostate volume and number of increases in the PSA level from the initial prostate biopsy were predictors for prostate cancer diagnosis at the second prostate biopsy. In patients with a steady PSA increase after the initial prostate biopsy, prostate volume and number of biopsy cores were predictors for prostate cancer diagnosis at the second prostate biopsy.

conclusionThe indications for a second prostate biopsy are a low prostate volume and a high number of increases in the PSA level among patients with a PSA decrease at the first follow-up and a low prostate volume and a high number of biopsy cores among patients with a PSA increase at the first follow-up.

Indexed as

Biopsy coresProstate biopsyProstate-specific antigen

Identifiers

PMID28352620
PMCPMC5357971
OpenAlexW2566665866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.