Evidence map›Paper›PMID 28352471›Full record

ArticleCanine genetics and epidemiology2017

Genetic mapping of principal components of canine pelvic morphology.

Mark J Fealey, Joy Li, Rebel J E Todhunter, Ursula Krotscheck, Kei Hayashi, Marina J McConkey, Adam R Boyko, Jessica J Hayward, Rory J Todhunter

Open access · goldAbstract read
In one paragraph

Article in Canine genetics and epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mark J FealeyDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Joy LiDepartment of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Rebel J E TodhunterDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Ursula KrotscheckDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Kei HayashiDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Marina J McConkeyDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Adam R BoykoDepartment of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Jessica J HaywardDepartment of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Rory J TodhunterDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 USA.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConcentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behavioral phenotypes. We explored the relationship between pelvic conformation and canine hip dysplasia (HD) because purebred dogs which are predisposed, or not, to HD share common morphologic features, respectively. Thirteen unique bilateral anatomical features of the pelvis were measured on 392 dogs of 51 breeds and 95 mixed breed dogs. Principal components (PCs) were derived to describe pelvic morphology. Dogs were genotyped at ~183,000 single nucleotide polymorphisms and their hip conformation was measured by the Norberg angle and angle of inclination between the femoral neck and diaphysis.

resultsNo associations reached genome wide significance for the Norberg angle when averaged over both hips. PC1 was negatively correlated with the Norberg angle (

conclusion

Indexed as

DogGWASHip dysplasiaIGF-1Norberg anglePelvic sexual dimorphismPrincipal component analysis

Identifiers

PMID28352471
PMCPMC5364603
OpenAlexW2600840119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.