Evidence map›Paper›PMID 28352430›Full record

ArticleCardiology research2013

Congenital Thrombophilia and Intracardiac Thrombosis: Probably an Underdiagnosed Event.

Antonio Girolami, Giulia Berti de Marinis, Martina Treleani, Valentina Tasinato, Bruno Girolami

Open access · hybridAbstract read
In one paragraph

Article in Cardiology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Antonio GirolamiDepartment of Medicine, University of Padua, Medical School, Padua, Italy.
Giulia Berti de MarinisDepartment of Medicine, University of Padua, Medical School, Padua, Italy.
Martina TreleaniDepartment of Medicine, University of Padua, Medical School, Padua, Italy.
Valentina TasinatoDepartment of Medicine, University of Padua, Medical School, Padua, Italy.
Bruno GirolamiDivision of General Medicine, Padua City Hospital, Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the number of patients with congenital thrombophilia who presented an intracardiac thrombosis.

methodsPersonal files were reevaluated together with a time-unlimited search of the literature.

resultsTwenty-five patients with intracardiac thrombosis and congenital thrombophilia have been gathered from the literature including the two personal cases. The distribution observed in thrombophilia patients is similar for left side or right side heart (9 vs 11 cases). The left ventricle and the right ventricle were involved in six or five instances, respectively. In one case, both ventricles were involved. On the contrary, the left atrium was involved in three cases whereas the right atrium was affected in six cases. In the remaining cases, more than one heart chamber was involved.

conclusionsIn "normal" subjects, left side thromboses are predominant once catheter-associated thrombi are excluded. The reason of this discrepancy lies in the greater prothrombotic effect exercised by congenital thrombophilia on venous thrombosis compared to arterial thrombosis. The relative high prevalence of cardiac thrombosis seen in patients with antithrombin and protein C deficiencies indicated that a cardiac evaluation should be carried out in all patients with these two defects.

Indexed as

Antithrombin deficiencyCardiac thrombosisProtein C deficiencyThrombophilia

Identifiers

PMID28352430
PMCPMC5358248
OpenAlexW2137073390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.