Evidence map›Paper›PMID 28352333›Full record

ArticleExperimental and therapeutic medicine2017

Protective effects and mechanism of TPX2 on neurocyte apoptosis of rats in Alzheimer's disease model.

Keshan Liang, Jingling Zhang, Chengbin Yin, Xueying Zhou, Shengnian Zhou

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Keshan LiangDepartment of Neurology, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, Shandong 250012, P.R. China; Department of Neurology, Pingyi Branch of Qilu Hospital, Shandong University, Pingyi, Shandong 273300, P.R. China.
Jingling ZhangDepartment of Endocrinology, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China.
Chengbin YinDepartment of Emergency, Qingdao Branch of Qilu Hospital of Shandong University, Qingdao, Shandong 266000, P.R. China.
Xueying ZhouDepartment of Neurology, Shangdong University of Traditional Chinese Medicine, Jinan, Shandong 250031, P.R. China.
Shengnian ZhouDepartment of Neurology, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, Shandong 250012, P.R. China.
Qilu Hospital of Shandong University · CNLinyi People's Hospital · CNShandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the protective effects and mechanism of TPX2 on apoptosis of rat neurocytes. A total of 90 SD rats were randomly divided into the drug group, the control group and the blank group, with 30 rats in each group. The rats in the drug group and in the blank group were anesthetized with 10% chloral hydrate (at the dose of 0.5 ml/100 g) and Aβ

Indexed as

Alzheimer's diseaseapoptosisMAPKTPX2

Identifiers

PMID28352333
PMCPMC5348683
OpenAlexW2567031164

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.