Evidence map›Paper›PMID 28352236›Full record

ReviewFrontiers in physiology2017

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype.

Sukriti Dewan, Kimberly J McCabe, Michael Regnier, Andrew D McCulloch

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  5. Review
  6. A review of inflammatory mechanism in airway diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sukriti DewanDepartments of Bioengineering and Medicine, University of California San Diego, La Jolla, CA, USA.
Kimberly J McCabeDepartments of Bioengineering and Medicine, University of California San Diego, La Jolla, CA, USA.
Michael RegnierDepartments of Bioengineering and Medicine, University of Washington Seattle, WA, USA.
Andrew D McCullochDepartments of Bioengineering and Medicine, University of California San Diego, La Jolla, CA, USA.
University of California, San Diego · USUniversity of Washington · US

Funding

National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
Analyzing the Cardiac Power Grid: Adaptive responses to fluctuating local demandU01HL122199 · NHLBI · UNIVERSITY OF WASHINGTON · PI BEARD, DANIEL A, DASH, RANJAN K · 2015 to 2019
$3.3M
Systems Biology of Hypertrophic Heart Disease from Molecular Pathways to Organ SystemR01HL137100 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D. · 2017 to 2020
$2.0M
NHLBI NIH HHS R01 HL137100NHLBI NIH HHS U01 HL122199NIGMS NIH HHS P41 GM103426
6 · The paper itself

Abstract

Dilated Cardiomyopathy (DCM) is a leading cause of sudden cardiac death characterized by impaired pump function and dilatation of cardiac ventricles. In this review we discuss various

Indexed as

cross-bridgedilated cardiomyopathyMarkovmechanicsmodelingmyofilamentTropomyosintroponin

Identifiers

PMID28352236
PMCPMC5348544
OpenAlexW2595885983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.