Evidence map›Paper›PMID 28352175›Full record

ArticleInternational journal of nanomedicine2017

Factors influencing transfection efficiency of pIDUA/nanoemulsion complexes in a mucopolysaccharidosis type I murine model.

Michelle Fraga, Talita Giacomet de Carvalho, Juliana Bidone, Roselena Silvestri Schuh, Ursula Matte, Helder Ferreira Teixeira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Lipid carriers for mRNA delivery.Acta pharmaceutica Sinica. B · 2023
    Review
  2. Review
  3. Review
  4. Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management.International journal of molecular sciences · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Michelle FragaPharmaceutical Sciences Graduate Program, Universidade Federal do Rio Grande do Sul; Gene Therapy Center, Experimental Research Center, Hospital de Clínicas de Porto Alegre.
Talita Giacomet de CarvalhoGene Therapy Center, Experimental Research Center, Hospital de Clínicas de Porto Alegre; Genetics and Molecular Biology Graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Juliana BidonePharmaceutical Sciences Graduate Program, Universidade Federal do Rio Grande do Sul.
Roselena Silvestri SchuhPharmaceutical Sciences Graduate Program, Universidade Federal do Rio Grande do Sul; Gene Therapy Center, Experimental Research Center, Hospital de Clínicas de Porto Alegre.
Ursula MatteGene Therapy Center, Experimental Research Center, Hospital de Clínicas de Porto Alegre; Genetics and Molecular Biology Graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Helder Ferreira TeixeiraPharmaceutical Sciences Graduate Program, Universidade Federal do Rio Grande do Sul.
Hospital de Clínicas de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BRGene Therapy Laboratory · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucopolysaccharidosis type I (MPS I) is an autosomal disease caused by alpha-l-iduronidase (IDUA) deficiency. This study used

Indexed as

TransfectionAnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 MoleculeDisease Models, AnimalEmulsionsHumansIduronidaseImmunohistochemistryMiceMucopolysaccharidosis INanoparticlesPlasmidsReal-Time Polymerase Chain ReactionAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 antigen, humanCD68 MoleculeEmulsionsIduronidasecationic nanoemulsionsDSPE-PEGMPS IpIDUAplasmid

Identifiers

PMID28352175
PMCPMC5358998
OpenAlexW2601854017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.